Penicillin G sodium salt CAS: 69-57-8
MF: C16H17N2O4S•Na
MW: 356.37
A β-lactam antibiotic.

Penicillin G sodium salt (CAS 69-57-8)

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Synonym: Benzylpenicillin sodium salt
Application: A β-lactam antibiotic
CAS Number: 69-57-8
Molecular Weight: 356.37
Molecular Formula: C16H17N2O4S•Na
* Refer to Certificate of Analysis for lot specific data (including water content).
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Penicillin G sodium salt is a salt of Penicillin G. Penicillin G is a hydrophobic, β-lactam antibiotic produced by Penicillium spp.. As an antibiotic, Penicillin G is noted to posses effectiveness mainly against gram-positive organisms. Some gram-negative organisms such as Neiserria gonorrhoeae and Neiserria meningitidis are also reported to be susceptible to Penicillin G. Penicillin G is also known as benzylpenicillin and contains a 6′ phenylacetyl side chain. In acid aqueous solutions, Penicillin is reported to decompose into penillic acid and penilloic acid. Penicillin G is also available alone (sc-344973) and in salt form as Penicillin G potassium (sc-255411).


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2. Demain, A.L. 1991. Proc. Natl. Sci. Counc. Repub. China B. 15: 251-265. PMID: 1815263
3. Livermore, D.M. 2009. Curr. Protein Pept. Sci. 10: 397-400. PMID: 19538149

Appearance :
Physical State :
Solubility :
Soluble in water (100 mg/ml), alcohol, glycerol, DMSO (71 mg/ml at 25° C), and ethanol (< 1 mg/ml at 25° C).
Storage :
Store at 4° C
Melting Point :
227° C (lit.)
Boiling Point :
663.3° C at 760 mmHg
Density :
1.38 g/cm3
Refractive Index :
n20D ~1.66 (Predicted)
Optical Activity :
α20/D +297.5°±12.5°, c = 2 in water (Predicted)
Ki Data :
Solute carrier family 22 member 6: Ki= 328 µM (mouse); Solute carrier family 22 member 20: Ki= 452 µM (mouse)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
PubChem CID :
Merck Index :
14: 7094
MDL Number :
EC Number :
Beilstein Registry :
CC1([[email protected]@H](N2[[email protected]](S1)[[email protected]@H](C2=O)NC(=O)CC3=CC=CC=C3)C(=O)[O-])C.[Na+]

Download SDS (MSDS)

Certificate of Analysis

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