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Penicillin G potassium salt (CAS 113-98-4)

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Alternate Names:
Benzylpenicillin Potassium Salt
Application:
Penicillin G potassium salt is a β-lactam antibiotic
CAS Number:
113-98-4
Molecular Weight:
372.48
Molecular Formula:
C16H17KN2O4S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Penicillin G potassium salt is a widely studied form of penicillin used extensively in microbiological research for its antibacterial activity. Researchers utilize this compound to investigate the mechanisms of bacterial growth inhibition, particularly in gram-positive organisms, where it disrupts cell wall synthesis. In molecular biology, it serves as a selective agent to maintain the growth of penicillin-resistant strains of bacteria or to ensure the purity of bacterial cultures by eliminating contaminating susceptible strains. This potassium salt form offers enhanced solubility, making it suitable for use in various aqueous media, including growth media and experimental buffers. Additionally, its role in the study of bacterial resistance mechanisms is crucial, as it helps in understanding how resistance genes are transferred and expressed within microbial communities.


Penicillin G potassium salt (CAS 113-98-4) References

  1. Pharmacokinetics of penicillin G procaine versus penicillin G potassium and procaine hydrochloride in horses.  |  Uboh, CE., et al. 2000. Am J Vet Res. 61: 811-5. PMID: 10895905
  2. MECHANISM OF DEGRADATION OF PENICILLIN G IN ACIDIC SOLUTION.  |  SCHWARTZ, MA. 1965. J Pharm Sci. 54: 472-3. PMID: 14301592
  3. Evaluation of the effects of penicillin G potassium and potassium chloride on the motility of the large intestine in horses.  |  Roussel, AJ., et al. 2003. Am J Vet Res. 64: 1360-3. PMID: 14620770
  4. Flow-injection-chemiluminescence method for the determination of penicillin G potassium.  |  Cao, W., et al. 2005. Luminescence. 20: 238-42. PMID: 16134206
  5. Production of beta-lactam antibiotics and its regulation.  |  Demain, AL. 1991. Proc Natl Sci Counc Repub China B. 15: 251-65. PMID: 1815263
  6. The role of penicillin G potassium in managing Clostridium perfringens in broiler chickens.  |  Gadbois, P., et al. 2008. Avian Dis. 52: 407-11. PMID: 18939627
  7. beta-Lactamases- the Threat Renews.  |  Livermore, DM. 2009. Curr Protein Pept Sci. 10: 397-400. PMID: 19538149
  8. Direct chemiluminescence determination of penicillin G potassium and a chemometrical optimization approach.  |  Sorouraddin, MH., et al. 2011. Luminescence. 26: 622-8. PMID: 21465632
  9. Penicillin G as a novel chiral selector in capillary electrophoresis.  |  Dixit, S. and Park, JH. 2014. J Chromatogr A. 1326: 134-8. PMID: 24373536
  10. Efficient cascade synthesis of ampicillin from penicillin G potassium salt using wild and mutant penicillin G acylase from Alcaligenes faecalis.  |  Deng, S., et al. 2016. J Biotechnol. 219: 142-8. PMID: 26732414
  11. Preparation of three-dimensional ordered macroporous Ag/LaFeO3 and heterogeneous photo-Fenton degradation of penicillin G potassium.  |  Zhang, Q., et al. 2022. Environ Technol. 1-17. PMID: 35959951
  12. pH-dependent effect of magnesium sulfate on the stability of penicillin G potassium solution.  |  Das Gupta, V. and Stewart, KR. 1985. Am J Hosp Pharm. 42: 598-602. PMID: 3985024
  13. Separation of penicillin G potassium and its degradation products using high-pressure liquid chromatography.  |  Vadino, WA., et al. 1979. J Pharm Sci. 68: 1316-8. PMID: 512869

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Penicillin G potassium salt, 250 mg

sc-255411
250 mg
$45.00

Penicillin G potassium salt, 5 g

sc-255411A
5 g
$70.00