PEG NHS ester disulfide (n=7) (CAS 947601-98-1)
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PEG NHS ester disulfide (n=7), with a polyethylene glycol (PEG) chain of seven repeating units, is a compound utilized in biochemical and materials research for its ability to modify proteins and peptides. The NHS (N-hydroxysuccinimide) ester is reactive towards amine groups, allowing for the covalent attachment of the PEG chain to biomolecules, a process known as PEGylation. This modification is studied for its effects on the solubility, stability, and bioactivity of proteins. The disulfide bond in the compound provides a cleavable linker that is sensitive to reducing conditions. In addition, PEG NHS ester disulfide (n=7) is used in the preparation of surface coatings for nanoparticles or other materials to improve their biocompatibility and reduce nonspecific interactions with biological components.
PEG NHS ester disulfide (n=7) (CAS 947601-98-1) References
- Label-free sensing of adenosine based on force variations induced by molecular recognition. | Li, J., et al. 2015. Biosensors (Basel). 5: 85-97. PMID: 25808841
- A novel aptasensor based on single-molecule force spectroscopy for highly sensitive detection of mercury ions. | Li, Q., et al. 2015. Analyst. 140: 5243-50. PMID: 26075518
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PEG NHS ester disulfide (n=7), 100 mg | sc-236303 | 100 mg | $230.00 |