Pefloxacin mesylate dihydrate (CAS 149676-40-4)

Pefloxacin mesylate dihydrate, a derivative of quinolone antibiotic pefloxacin, has garnered interest in research due to its antimicrobial properties. Its mechanism involves inhibition of bacterial DNA gyrase, crucial for DNA replication, thus impeding bacterial growth. Research has explored its efficacy against various bacterial strains, particularly those exhibiting resistance to other antibiotics. Studies have investigated its role in treating infections in animal models, assessing pharmacokinetics, and exploring potential synergistic effects with other antimicrobial agents. Furthermore, research delves into elucidating its molecular interactions with bacterial enzymes and DNA, shedding light on its mode of action and potential for drug development. Additionally, investigations into its pharmacological profile, including absorption, distribution, metabolism, and excretion, contribute to understanding its suitability for diverse research applications. Ongoing studies aim to expand knowledge of pefloxacin mesylate dihydrate′s antimicrobial activity, pharmacokinetics, and mechanism of action, fostering its utility as a valuable tool in microbiological and pharmacological research endeavors.