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PDGFRβ/RAF Kinase Inhibitor is an orally bioavailable amino-triazole compound that is shown to bind to the inactive conformations of both PDGFRβ and Raf kinases (allosteric, Type II inh), and acts as a potent inhibitor of Flt3, Kit, PDGFRα and PDGFRβ (Kd = 52, 170, 300 and 520 nM, respectively) with selectivity over B-Raf, p38α, FGFR2 and VEGFR2 (Kd > 10 µM) in a multi-kinase panel.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PDGFRβ/RAF Kinase Inhibitor, 10 mg | sc-364570 | 10 mg | $319.00 |