Pdcd2L Antibody (K-13): sc-101251

Pdcd2L Antibody (K-13) is a mouse monoclonal IgG1 kappa light chain antibody that detects Pdcd2L in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-Pdcd2L antibody (K-13) is available as a non-conjugated format, providing researchers with a versatile tool for studying this important protein. Pdcd2L, also known as programmed cell death 2-like, consists of 358 amino acids and shares significant homology with Pdcd-2, a protein involved in the regulation of apoptosis. Pdcd2L monoclonal antibody (K-13) recognizes a protein primarily expressed in the placenta, heart, pancreas, lung, and liver, with lower levels found in the spleen, lymph nodes, and thymus. Pdcd2L expression is crucial as this protein may play a role in modulating apoptotic pathways, which are vital for maintaining cellular homeostasis and preventing uncontrolled cell proliferation. Understanding Pdcd2L function and interactions within apoptotic signaling networks can provide insights into various diseases, including cancer and autoimmune disorders, making Pdcd2L (K-13) antibody an essential reagent for researchers investigating these critical biological processes.

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Pdcd2L Antibody (K-13) References:

1. Characterization of a novel mouse cDNA, ES18, involved in apoptotic cell death of T-cells.  |  Park, EJ., et al. 1999. Nucleic Acids Res. 27: 1524-30. PMID: 10037816
2. Increased expression of apoptosis-linked gene 2 (ALG2) in the rat brain after temporary focal cerebral ischemia.  |  Li, W., et al. 2000. Neuroscience. 96: 161-8. PMID: 10683420
3. PD-L2 is a second ligand for PD-1 and inhibits T cell activation.  |  Latchman, Y., et al. 2001. Nat Immunol. 2: 261-8. PMID: 11224527
4. Induced expression of PD-1, a novel member of the immunoglobulin gene superfamily, upon programmed cell death.  |  Ishida, Y., et al. 1992. EMBO J. 11: 3887-95. PMID: 1396582
5. Alterations of DNA copy number and expression in genes involved in cell cycle regulation and apoptosis signal pathways in gamma-radiation-sensitive SX9 cells and -resistant SR-1 cells.  |  Koshikawa, T., et al. 2005. Radiat Res. 163: 374-83. PMID: 15799692
6. Coordination of intrinsic, extrinsic, and endoplasmic reticulum-mediated apoptosis by imatinib mesylate combined with arsenic trioxide in chronic myeloid leukemia.  |  Du, Y., et al. 2006. Blood. 107: 1582-90. PMID: 16249384
7. Cloning of cDNAs with PDCD2(C) domain and their expressions during apoptosis of HEK293T cells.  |  Chen, Q., et al. 2005. Mol Cell Biochem. 280: 185-91. PMID: 16311922
8. Deregulated stress system in non-obese diabetic lymphocyte.  |  Liu, Z. and Aune, TM. 2006. Genes Immun. 7: 352-8. PMID: 16691184
9. Expression of the PD-1 antigen on the surface of stimulated mouse T and B lymphocytes.  |  Agata, Y., et al. 1996. Int Immunol. 8: 765-72. PMID: 8671665

Monoclonal antibodies for mammalian and non-mammalian protein targets represent essentially all targets covered by polyclonal antibodies. Over 8,300 of our antibodies are offered as ImmunoCruz^® conjugates which eliminates the need for a secondary antibody.

Santa Cruz Biotechnology antibodies have over 360,000 research citations. Anti-Pdcd2L Antibody (K-13) has 1 citations in a variety of scientific publications.

Primary antibodies like Anti-Pdcd2L Antibody (K-13) for mammalian target proteins are recommended for the detection of a range of mammalian species, primarily of mouse, rat and human species. Many mammalian antibodies are also ideal for veterinary research and reactive with ovine, porcine, caprine, feline, canine, bovine and equine protein targets. Santa Cruz Biotechnology primary monoclonal antibodies are suitable for laboratory research applications and are not intended for diagnostic or therapeutic use.

Pdcd2L Antibody (K-13) Specifications

Alternate Product Name: Pdcd2L

Product Clone Name: K-13

Classification: Primary Antibody

Clonality: Monoclonal Antibody

Antibody Isotype: IgG₁ kappa light chain

Amino Acids: 80-179

Epitope Target: Pdcd2L

Epitope Species: human

Product Reactivity/Detection: Pdcd2L

Species Reactivity/Detection: mouse, rat, human

Additional Mammalian Reactivity: N/A

Additional Non-Mammalian Reactivity: N/A

Applications: WB, IP, IF, ELISA

Vialing Information: Each vial contains 100 µg IgG₁ kappa light chain in 1.0 ml of PBS with < 0.1% sodium azide and 0.1% gelatin

Research Citations: 1 citations in various scientific publications

Available Conjugates/Forms for Pdcd2L Antibody (K-13): N/A