Molecular structure of PD 168077 maleate, CAS Number: 190383-31-4
PD 168077 maleate (CAS 190383-31-4)
Alternate Names:
N-(Methyl-4-(2-cyanophenyl)piperazinyl-3-methylbenzamide maleate
Application:
PD 168077 maleate is a potent and selective agonist of the dopamine D4 receptor
CAS Number:
190383-31-4
Purity:
≥99%
Molecular Weight:
450.49
Molecular Formula:
C20H22N4O•C4H4O4
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
PD 168077 maleate is a D4DR (D4 dopamine) agonist. >400-fold selectivity over D2 with >300-fold selectivity v.s. D3 subtypes. Generates synaptic translocation of CaMK II to postsynaptic sites in cultured prefrontal cortical neurons.
PD 168077 maleate (CAS 190383-31-4) References
- Effect of selective dopamine D3 and D4 receptor agonists on trunk pulmonary artery vascular reactivity from control and monocrotaline-treated rats. | de Jesus, L., et al. 2022. J Physiol Pharmacol. 73: PMID: 36515630
Activator of:
D3DR, and D4DR.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
PD 168077 maleate, 10 mg | sc-204165 | 10 mg | $371.00 | |||
PD 168077 maleate, 50 mg | sc-204165A | 50 mg | $1450.00 |