Molecular structure of Pazufloxacin Mesylate, CAS Number: 163680-77-1
Pazufloxacin Mesylate (CAS 163680-77-1)
Alternate Names:
Pazufloxacin methanesulfonate
Application:
Pazufloxacin Mesylate is a fluoroquinolone antimicrobial agent
CAS Number:
163680-77-1
Purity:
98%
Molecular Weight:
414.41
Molecular Formula:
C17H19FN2O7S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Pazufloxacin mesylate, referred to as PZM, is a synthetic fluoroquinolone antibiotic. This advanced iteration of the fluoroquinolone class surpasses its predecessor, ciprofloxacin, in terms of efficacy, boasting an extended half-life. In vitro investigations have assessed its antibacterial activity and its potential to impede the growth of specific bacterial strains. Although the precise mechanism of action for Pazufloxacin mesylate remains incompletely elucidated, current understanding suggests its operation by inhibiting bacterial DNA gyrase—a enzyme involved in DNA replication. Through this inhibition, Pazufloxacin mesylate hinders bacterial replication, leading to the demise of the bacteria.
Pazufloxacin Mesylate (CAS 163680-77-1) References
- Effect of pazufloxacin mesilate on the serum concentration of theophylline. | Niki, Y., et al. 2002. J Infect Chemother. 8: 33-6. PMID: 11957117
- [In vitro and in vivo antibacterial activities of pazufloxacin mesilate, a new injectable quinolone]. | Nomura, N., et al. 2002. Jpn J Antibiot. 55: 412-39. PMID: 12378871
- [Pharmacological properties and expected clinical role of an injectable new quinolone antibiotic, pazufloxacin mesilate]. | Minami, S., et al. 2003. Nihon Yakurigaku Zasshi. 122: 161-78. PMID: 12890902
- Terbium-sensitized fluorescence method for the determination of pazufloxacin mesilate and its application. | Chen, S., et al. 2004. Anal Sci. 20: 1075-8. PMID: 15293405
- [Effect of pazufloxacin mesilate, a new quinolone antibacterial agent, for intravenous use on QT interval]. | Fukuda, H., et al. 2004. Jpn J Antibiot. 57: 404-12. PMID: 15535041
- Efficacy of pazufloxacin mesilate in Legionnaires' disease: a case report and in vitro study of the isolate. | Higa, F., et al. 2005. J Infect Chemother. 11: 164-8. PMID: 15990982
- Preparation and characterization of glutaraldehyde cross-linked O-carboxymethylchitosan microspheres for controlled delivery of pazufloxacin mesilate. | Liu, YF., et al. 2007. Int J Biol Macromol. 41: 87-93. PMID: 17292465
- Influence of cefoperazone and azithromycin on the pharmacokinetics of pazufloxacin in rats. | Lou, S., et al. 2007. Eur J Drug Metab Pharmacokinet. 32: 219-23. PMID: 18348471
- [Clinical pharmacokinetics/pharmacodynamics study on pazufloxacin methanesulphonate injection]. | Wang, XG., et al. 2009. Sichuan Da Xue Xue Bao Yi Xue Ban. 40: 689-93. PMID: 19764574
- [Evaluation of target attainment rate of pazufloxacin mesilate using Monte Carlo simulation method]. | Abe, N., et al. 2010. Jpn J Antibiot. 63: 319-25. PMID: 21298865
- Adsorption behavior of pazufloxacin mesilate on amino-functionalized carbon nanotubes. | Jiang, L., et al. 2012. J Nanosci Nanotechnol. 12: 7271-9. PMID: 23035463
- A fluorescence probe based on biomolecule-stabilized gold nanoclusters for the detection of pazufloxacin mesilate. | Cao, X., et al. 2014. Anal Sci. 30: 817-22. PMID: 25109644
- Effects of repeated oral administration of pazufloxacin mesylate and meloxicam on the antioxidant status in rabbits. | Khan, AM. and Rampal, S. 2014. J Am Assoc Lab Anim Sci. 53: 399-403. PMID: 25199097
- Colorimetric recognition of pazufloxacin mesilate based on the aggregation of gold nanoparticles. | Kong, S., et al. 2016. Spectrochim Acta A Mol Biomol Spectrosc. 157: 244-250. PMID: 26774816
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Pazufloxacin Mesylate, 1 g | sc-205793A | 1 g | $131.00 | |||
Pazufloxacin Mesylate, 5 g | sc-205793 | 5 g | $287.00 |