Parvovirus Antibody (8H7): sc-52146

Parvovirus Antibody (8H7) is a mouse monoclonal IgG2a antibody that detects Parvovirus, specifically targeting Parvovirus B19, and is suitable for use in enzyme-linked immunosorbent assay (ELISA) applications. Parvovirus B19 is a member of the Parvoviridae family and is known for its small size and unique structure, which is critical for its function as a viral pathogen. The viral capsid is composed of three proteins—VP1, VP2, and VP3—that assemble into a robust icosahedral structure, providing stability against environmental factors such as pH changes and temperature fluctuations up to 50°C. This structural resilience is essential for the virus′s ability to infect host cells, as Parvovirus B19 protects the viral genome during transmission and entry into the host. Once inside the host, the single-stranded DNA genome, which is approximately 5 kilobases in length, is released and can hijack the host′s cellular machinery to replicate. Parvovirus B19 primarily infects erythroid progenitor cells in the bone marrow, leading to conditions such as aplastic crisis in individuals with underlying hemolytic anemia. Understanding the structure and function of Parvovirus B19 remains crucial, particularly in clinical settings where Parvovirus B19 poses significant risks, such as in pregnant women who may transmit the virus to their fetuses, potentially resulting in severe complications. Anti-Parvovirus antibody (8H7) serves as a valuable tool for researchers studying this virus and its interactions within the host.

The preferred Parvovirus antibody is Parvovirus Antibody (CPV1-2A1): sc-57961.