Paromomycin Sulfate (CAS 1263-89-4)
QUICK LINKS
Paromomycin sulfate is an aminoglycoside antibiotic used in research applications that focus on the inhibition of protein synthesis in prokaryotic organisms. It is frequently employed in microbiological studies to investigate the efficacy and specificity of antibacterial agents against a variety of bacterial strains. In molecular biology, paromomycin sulfate is utilized to induce miscoding during translation in cell-free systems, which helps in understanding the fidelity of protein synthesis. In addition, researchers use this compound in the study of ribosomal structure and function, as it binds to the rRNA of the small ribosomal subunit, affecting the decoding site. Studies involving the compound also extend to environmental microbiology, where it is used to assess the impact of aminoglycosides on microbial communities and the development of resistance in natural and artificial ecosystems.
Paromomycin Sulfate (CAS 1263-89-4) References
- Effects of paromomycin sulfate in man against Entamoeba histolytica and other intestinal protozoa. | CARTER, CH., et al. 1962. Am J Trop Med Hyg. 11: 448-51. PMID: 13876942
- Effect of topical liposomes containing paromomycin sulfate in the course of Leishmania major infection in susceptible BALB/c mice. | Jaafari, MR., et al. 2009. Antimicrob Agents Chemother. 53: 2259-65. PMID: 19223613
- Combination therapy with paromomycin-associated stearylamine-bearing liposomes cures experimental visceral leishmaniasis through Th1-biased immunomodulation. | Banerjee, A., et al. 2011. Antimicrob Agents Chemother. 55: 1661-70. PMID: 21220536
- Effect of topical Nanoliposomes of Paromomycin on Rats Liver and Kidney. | Kalantari, H., et al. 2014. Jundishapur J Nat Pharm Prod. 9: e17565. PMID: 25625051
- Drug Targeting to Macrophages With Solid Lipid Nanoparticles Harboring Paromomycin: an In Vitro Evaluation Against L. major and L. tropica. | Kharaji, MH., et al. 2016. AAPS PharmSciTech. 17: 1110-9. PMID: 26552399
- Solid lipid nanoparticle loaded with paromomycin: in vivo efficacy against Leishmania tropica infection in BALB/c mice model. | Heidari-Kharaji, M., et al. 2016. Appl Microbiol Biotechnol. 100: 7051-60. PMID: 26960322
- Characterization of the binding of neomycin/paromomycin sulfate with DNA using acridine orange as fluorescence probe and molecular docking technique. | Zhou, H., et al. 2017. J Biomol Struct Dyn. 35: 2077-2089. PMID: 27392082
- Paromomycin sulfate is an effective treatment for balantidiasis in captive cynomolgus monkeys. | Nakamura, S., et al. 2019. Exp Anim. 68: 285-292. PMID: 30814394
- Nanoemulsions with Chloroaluminium Phthalocyanine and Paromomycin for Combined Photodynamic and Antibiotic Therapy for Cutaneous Leishmaniasis. | Leal Pinto, SM., et al. 2021. Infect Chemother. 53: 342-354. PMID: 34216127
- Paromomycin Sulfate Treatment in Histomoniasis Outbreaks in Three Commercial Turkey Flocks in the Fraser Valley of British Columbia, Canada. | Lin, GW. 2021. Avian Dis. 65: 592-598. PMID: 35068103
- [Efficacy of paromomycin sulfate against human cestodiasis and its pharmacological action on tapeworm in vitro]. | Niimura, M., et al. 1983. Jpn J Antibiot. 36: 594-601. PMID: 6876366
- [Effects of paromomycin sulfate on Diphyllobothrium latum infections]. | Nagase, K., et al. 1983. Jpn J Antibiot. 36: 615-8. PMID: 6876369
- Antimicrobial susceptibility of bifidobacteria. | Lim, KS., et al. 1993. J Dairy Sci. 76: 2168-74. PMID: 8408866
- A chemical assessment and HPLC assay validation of bulk paromomycin sulfate. | Olson, LL., et al. 1997. J Pharm Biomed Anal. 15: 783-93. PMID: 9172104
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Paromomycin Sulfate, 1 g | sc-204832 | 1 g | $75.00 | |||
Paromomycin Sulfate, 5 g | sc-204832A | 5 g | $185.00 |