Paraoxon is an organophosphate pesticide. Paraoxon can function as a surrogate of chemical warfare agents. Using titania nanoparticles, Paraoxon can undergo degradation while immobilized on quartz or glass substrates. Paraoxon is a known metabolite of parathion. Paraoxon also is used as an irreversible acetylcholinesterase inhibitor.
1. Pickering, W.R., et al.: Biochem. Pharmacol., 16, 1183 (1967) 2. Photocatalytic degradation of paraoxon-ethyl in aqueous solution using titania nanoparticulate film Prasad.K.G, et al. Thin Solid Films 520(17), 5597-5601, (2012) 3. Improvement of acetylcholinesterase-based assay for organophosphates in way of identification by reactivators Pohanka M, et al. Talanta 77(1), 451-454, (2008) 4. S K Falahati-Pour et. al Journal of applied microbiology, 118(4), undefined (2015-1-8) 5. Nobuhiko Tokuriki et. al Nature communications, 3, undefined (2012-12-6)
Soluble in chloroform, ether, hexane, and water (2.4 mg/ml).
Rated 5 out of
JanJan, YH. et al. (PubMed 26212258) demonstrate that menadione is a potent inhibitor of cytochrome P450-mediated metabolism of parathion to its cytotoxic metabolite Paraoxon, a cholinesterase inhibitor. -SCBT Publication Review
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