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Paramethasone Acetate (CAS 1597-82-6)

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Alternate Names:
(6α,11β,16α)-21-(Acetyloxy)-6-fluoro-11,17-dihydroxy-16-methylpregna-1,4-diene-3,20-dione; 16α-Methyl-6α-fluoroprednisolone 21-acetate
CAS Number:
1597-82-6
Molecular Weight:
434.50
Molecular Formula:
C24H31FO6
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Paramethasone Acetate is a synthetic corticosteroid with glucocorticoid activity utilized in various research applications. In studies of anti-inflammatory mechanisms, Paramethasone Acetate provides a means to investigate the modulation of cytokine production and the inhibition of inflammatory mediator release. It is also used in research concerning the regulation of gene expression by glucocorticoid receptor-mediated pathways. In cellular and molecular biology experiments, Paramethasone Acetate serves as a tool to study the effects of glucocorticoids on cell proliferation, apoptosis, and differentiation processes. Furthermore, its role in the induction of certain enzymes involved in metabolic pathways is examined to understand the broader implications of steroid hormone action. The acetate form of Paramethasone is often selected for its enhanced solubility and stability, making it suitable for in vitro assays and experimental models that require precise control of corticosteroid concentration.


Paramethasone Acetate (CAS 1597-82-6) References

  1. Inflammatory linear verrucose epidermal nevus.  |  Toribio, JT. and Quicres, PA. 1975. Dermatologica. 150: 65-9. PMID: 1158005
  2. Effect of paramethasone acetate on ovarian steroids and gonadotropins. I. Normal menstrual cycle.  |  Cortés-Gallegos, V., et al. 1975. J Clin Endocrinol Metab. 41: 215-20. PMID: 1159039
  3. Clinical assessment of a new corticosteroid: paramethasone acetate.  |  ANDERSON, R. and JAMES, DG. 1963. Practitioner. 190: 632-5. PMID: 14012903
  4. [Paramethasone acetate in the treatment of the nephrotic syndrome in children].  |  CHEN, CH. 1962. Zhonghua Min Guo Xiao Er Ke Yi Xue Hui Za Zhi. 3: 114-7. PMID: 14020489
  5. [CLINICAL TRIAL OF PARAMETHASONE ACETATE IN PEDIATRICS].  |  FURUKAWA, W. and TAKEUCHI, T. 1964. Chiryo. 46: 780-4. PMID: 14148039
  6. [Clinical study of injectable paramethasone acetate: comparative study on the therapeutic effect of 6-alpha-fluoro-16-alpha-methyl-prednisolone-21-acetate administered orally and parenterally].  |  Menarini, C. and Lanzarini, AM. 1971. Clin Ter. 59: 499-505. PMID: 5143383
  7. [Paramethasone acetate in pediatrics].  |  Maillard, E. and Fontaine, G. 1967. Lille Med. 12: Suppl:1129-33. PMID: 5310464
  8. [Injectable paramethasone acetate in surgical practice].  |  Desbrosses, J. 1970. Lyon Med. 224: 741-3. PMID: 5485437
  9. Paramethasone acetate (PA): corticosteroid potency vs hypothalamic pituitary-gonadal axis.  |  Cortés-Gallegos, V., et al. 1984. J Steroid Biochem. 20: 353-6. PMID: 6423900
  10. Effect of paramethasone acetate upon estrogen action.  |  Cortés-Gallegos, V., et al. 1982. Fertil Steril. 37: 402-5. PMID: 7060790
  11. Effect of paramethasone acetate on women with secondary amenorrhea: a preliminary report.  |  Cortés-Gallegos, V., et al. 1978. Fertil Steril. 29: 402-6. PMID: 77230
  12. Anaphylactic shock following povidone.  |  Gonzalo Garijo, MA., et al. 1996. Ann Pharmacother. 30: 37-40. PMID: 8773164
  13. Delayed local allergic reaction to intralesional paramethasone acetate.  |  Miranda-Romero, A., et al. 1998. Contact Dermatitis. 39: 31-2. PMID: 9686977

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Paramethasone Acetate, 5 mg

sc-477798
5 mg
$393.00