Molecular structure of Paraherquamide A, CAS Number: 77392-58-6
Paraherquamide A (CAS 77392-58-6)
Alternate Names:
Paraherquamide
Application:
Paraherquamide A is a selective, competitive, cholinergic antagonist
CAS Number:
77392-58-6
Purity:
>95%
Molecular Weight:
493.6
Molecular Formula:
C28H35N3O5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Paraherquamide A was first reported as a mycotoxin related to the indole tremorgenic mycotoxins. Subsequent research identified a potent non-toxic paralysis of nematodes which led to the metabolite′s development as a candidate anthelmintic. Paraherquamide A is a selective, competitive, cholinergic antagonist that distinguishes subtypes of cholinergic receptors.
Paraherquamide A (CAS 77392-58-6) References
1. Paraherquamide and 2-deoxy-paraherquamide distinguish cholinergic receptor subtypes in Ascaris muscle. Robertson A.P. et al. J. Pharmacol. Exp. Ther. 2002, 302, 853. 2. Novel antinematodal and antiparasitic agents from Penicillium charlesii I. Fermentation, isolation and biological activity. Ondeyka J.G. J. Antibiot. 1990, 43, 1375. 3. The structure of parherquamide, a toxic metabolite from Penicillium paraherquei. Yamazaki M.E. et al. Tetrahedron Lett. 1982, 22, 135.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Paraherquamide A, 1 mg | sc-202275 | 1 mg | $334.00 |