Paraformaldehyde CAS: 30525-89-4
MF: (CH2O)n
MW: 30.03 (as monomer)
A disinfectant and fixation reagent.

Paraformaldehyde (CAS 30525-89-4)

Paraformaldehyde | CAS 30525-89-4 is rated 4.7 out of 5 by 3.
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Synonym: Polyoxymethylene
Application: A disinfectant and fixation reagent
CAS Number: 30525-89-4
Purity: ≥88%
Molecular Weight: 30.03 (as monomer)
Molecular Formula: (CH2O)n
Supplemental Information: This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
* Refer to Certificate of Analysis for lot specific data (including water content).
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Paraformaldehyde has documented uses as a disinfectant, fungicide, fixation reagent and in the preparation of formaldehyde. In fluorescence studies, paraformaldehyde has been used as as a formalin fixative to fix cells and tissues. To use the chemical as a fixative, it must be converted to the monomer formaldehyde by heating as formaldehyde is the active chemical in fixation.


1. RICHARDSON, K.C. 1960. J. Anat. 94 : 457-472. PMID: 13741298
2. Carson, F.L. et al. 1973. Am. J. Clin. Pathol. 59(3): 365-373. PMID: 4119901

Usage :
For Use in Electron Microscopy

When using a formalin as a fixative in electron microscopy, the formalin must not contain methanol. Most commercial formalin contains methanol to prevent the formaldehyde from polymerizing. In electron microscopy studies, a fresh formalin solution can be prepared as follows:

1. Add desired amount of paraformaldehyde to a basic buffer or water.

2. Heat while stirring to 55-60°C until it dissolves and forms the formaldehyde solution.
Appearance :
Physical State :
Solubility :
Soluble in hot water, and many organic solvents. Insoluble in water, ether, and alcohol.
Storage :
Store at 4° C
Melting Point :
120-170° C (lit.)
Density :
0.88 g/cm3 at 25° C (lit.)
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
WGK Germany :
Transport :
UN 2213, Class 4.1, Packing group III
Merck Index :
14: 7025
MDL Number :
EC Number :
Beilstein Registry :

Download SDS (MSDS)

Certificate of Analysis

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Paraformaldehyde  Product Citations

See how others have used Paraformaldehyde. Click on the entry to view the PubMed entry .

Citations 1 to 10 of 18 total

PMID: # 29795281  Dorgau, B.|Felemban, M.|Sharpe, A.|Bauer, R.|Hallam, D.|Steel, DH.|Lindsay, S.|Mellough, C.|Lako, M.| et al. 2018. Cell Death Dis. 9: 615.

PMID: # 27992857  Moruno-Manchon, JF. et al. 2016. Aging (Albany NY). 8: 3507-3519.

PMID: # 26024892  Wedgwood, S. et al. 2015. Am. J. Physiol. Lung Cell Mol. Physiol. 309: L196-203.

PMID: # 10828033  Posey, SC.|Martelli, MP.|Azuma, T.|Kwiatkowski, DJ.|Bierer, BE.| et al. 2000. Blood. 95: 3483-8.

PMID: # 2254961  Keller, A. et al. 1990. Journal of neuroscience research. 27: 136-43.

PMID: # 29743316  J. Immunol. 201: 113-123.

PMID: # 31775907  Breast Cancer Res. 21: 125.

PMID: # 31580968  Biomaterials. 225: 119517.

PMID: # 31781107  Front Immunol. 10: 2603.

PMID: # 31831554  Clin. Cancer Res.

Citations 1 to 10 of 18 total

Hello, For reasons unknown Paraformaldehyd it's out of stock in my country and it seems the earliest delivery date is February 2019. I can't wait that long. Is Paraformaldehyde available? What would be the estimated delivery date? Best regards

Asked by: AMichalak
Thank you for your question. Please contact our European Support office to inquire about current product availability and shipping lead times.
Answered by: Technical Support
Date published: 2018-12-03

What is the shipping temperature for this product?

Asked by: hawkeye11
Thank you for your question. The compound, sc-253236, is shipped at ambient temperatures. If you have any further questions or concerns, please feel free to contact our Technical Service department by calling 800-457-3801 option 2, emailing [email protected], or using the Live Chat function on our website.
Answered by: Tech Service 8
Date published: 2017-02-10
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Rated 4 out of 5 by from Worked great Worked great!
Date published: 2015-10-28
Rated 5 out of 5 by from Use it routinely Use it routinely, works well.
Date published: 2015-04-29
Rated 5 out of 5 by from I have been using this product in the past I have been using this product in the past also and it's great.
Date published: 2015-03-24
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