pan nRNP Antibody (58-15-6) is a mouse monoclonal IgM antibody that detects pan nRNP in human samples through applications such as immunofluorescence (IF), immunohistochemistry with paraffin-embedded sections (IHCP), and flow cytometry (FCM). Anti-pan nRNP antibody (58-15-6) plays a crucial role in the study of autoimmune disorders, particularly those characterized by the presence of anti-nuclear antibodies, such as lupus erythematosus, Sjögren′s syndrome, autoimmune hepatitis, dermatomyositis, rheumatoid arthritis, and scleroderma. Pan nRNP (58-15-6) antibody targets a key component of the nucleolus involved in the formation of ribonucleoprotein (RNP) complexes, which are essential for various cellular processes, including RNA processing and transport. These complexes are composed of ribonucleic acid (RNA) and proteins, and their proper assembly is vital for maintaining cellular homeostasis and regulating gene expression. The interaction between aromatic amino acid residues and RNA within the RNP motif facilitates critical stacking interactions, while lysine residues in the helical regions of RNA binding proteins enhance stability and specificity in nucleic acid binding. Pan nRNP (58-15-6) monoclonal antibody enables researchers to effectively investigate the dynamics of RNP complexes and their implications in the pathogenesis of autoimmune diseases, thereby advancing our understanding of these complex disorders.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan nRNP Antibody (58-15-6) | sc-56750 | 100 µg/ml | $322.00 |