pan CEA Antibody (COL-1): sc-47756
- pan CEA Antibody (COL-1) is a mouse monoclonal IgG2a κ, cited in 3 publications, provided at 200 µg/ml
- raised against colon carcinoma cells of human origin
- recommended for detection of pan CEA of human origin by WB, IP, IF and IHC(P)
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for pan CEA Antibody (COL-1). This work is in progress.
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SEE ALSO...
pan CEA Antibody (COL-1) is a mouse monoclonal IgG2a antibody that detects carcinoembryonic antigen (CEA) in human samples through western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and immunohistochemistry. Anti-CEA antibody (COL-1) is particularly valuable in clinical diagnostics as CEA serves as a crucial tumor marker, primarily associated with colorectal cancer, but also relevant in other malignancies. CEA monoclonal antibody (COL-1) recognizes proteins predominantly located on the cell surface, where CEA plays a significant role in cell adhesion and signaling, which are essential for maintaining tissue architecture and facilitating communication between cells. This localization is vital for CEA′s involvement in processes such as tumor progression and metastasis, as CEA can influence the behavior of cancer cells and their interaction with the surrounding microenvironment. Additionally, human CEACAM proteins, including CEA, are encoded by genes clustered on chromosome 19, highlighting their evolutionary significance and potential as therapeutic targets. CEA (COL-1) antibody provides a powerful tool for researchers and clinicians aiming to understand CEA′s role in cancer biology and potential implications in patient management.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
pan CEA Antibody (COL-1) References:
- The carcinoembryonic antigen (CEA) family: structures, suggested functions and expression in normal and malignant tissues. | Hammarström, S. 1999. Semin Cancer Biol. 9: 67-81. PMID: 10202129
- Carcinoembryonic antigen (CEA) as tumor marker in lung cancer. | Grunnet, M. and Sorensen, JB. 2012. Lung Cancer. 76: 138-43. PMID: 22153832
- Serum levels of carcinoembryonic antigen (CEA) in patients with bipolar disorder. | Kaplan, I., et al. 2015. Acta Neuropsychiatr. 27: 177-81. PMID: 25697175
- Carcinoembryonic Antigen (CEA) and Hepatic Metastasis in Colorectal Cancer: Update on Biomarker for Clinical and Biotechnological Approaches. | Campos-da-Paz, M., et al. 2018. Recent Pat Biotechnol. 12: 269-279. PMID: 30062978
- Carcinoembryonic Antigen (CEA)-Specific 4-1BB-Costimulation Induced by CEA-Targeted 4-1BB-Agonistic Trimerbodies. | Mikkelsen, K., et al. 2019. Front Immunol. 10: 1791. PMID: 31417564
- DNA aptamers selection for carcinoembryonic antigen (CEA). | Izabella Abreu de Melo, M., et al. 2020. Bioorg Med Chem Lett. 30: 127278. PMID: 32527457
- Irisin and Carcinoembryonic Antigen (CEA) as Potential Diagnostic Biomarkers in Gastric and Colorectal Cancers. | Abd Temur, A. and Aqeel Rashid, F. 2021. Rep Biochem Mol Biol. 10: 488-494. PMID: 34981027
- Postoperative carcinoembryonic antigen (CEA) levels predict outcomes after resection of colorectal cancer in patients with normal preoperative CEA levels. | Zhang, C., et al. 2020. Transl Cancer Res. 9: 111-118. PMID: 35117164
- Carcinoembryonic antigen (CEA) levels in benign gastrointestinal disease states. | Loewenstein, MS. and Zamcheck, N. 1978. Cancer. 42: 1412-8. PMID: 361200
- Diagnostic Accuracy of Carcinoembryonic Antigen (CEA) in Detecting Colorectal Cancer Recurrence Depending on Its Preoperative Level. | Lee, TH., et al. 2023. J Gastrointest Surg. 27: 1694-1701. PMID: 37407895
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan CEA Antibody (COL-1) | sc-47756 | 200 µg/ml | $322.00 |