pan CEA Antibody (4/3/17): sc-53824
- pan CEA Antibody (4/3/17) is a mouse monoclonal IgG1 provided at 200 µg/ml
- raised against pan CEA from partially purified liver metastases of pan CEA of human origin
- recommended for detection of pan CEA of human origin by WB, IP and IF
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for pan CEA Antibody (4/3/17). This work is in progress.
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SEE ALSO...
pan CEA Antibody (4/3/17) is a mouse monoclonal IgG1 antibody that detects carcinoembryonic antigen (CEA) in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). Anti-CEA antibody (4/3/17) plays a crucial role in cancer diagnostics, as CEA is one of the most widely utilized tumor markers for assessing carcinomas in serum immunoassays. CEA is a member of the carcinoembryonic antigen-related cell adhesion molecule (CEACAM) family, characterized by a single N domain sharing structural homology with immunoglobulin variable domains, followed by a variable number of immunoglobulin constant-like A and/or B domains. The diverse functions of CEACAM proteins, including CEA, are vital for maintaining cellular integrity and function, involving processes such as tissue differentiation, three-dimensional structural arrangement, angiogenesis, apoptosis, and modulation of both innate and adaptive immune responses. Notably, human CEACAM proteins are encoded by genes clustered within a 1.2 Mb region on the long arm of chromosome 19, highlighting their evolutionary significance and potential implications in cancer biology. CEA monoclonal antibody (4/3/17) serves as an essential tool for researchers and clinicians exploring CEA′s role in tumor biology and potential as a therapeutic target.
Alexa Fluor® is a trademark of Molecular Probes Inc., OR., USA
LI-COR® and Odyssey® are registered trademarks of LI-COR Biosciences
pan CEA Antibody (4/3/17) References:
- Carcinoembryonic antigen (CEA) levels in hookah smokers, cigarette smokers and non-smokers. | Sajid, KM., et al. 2007. J Pak Med Assoc. 57: 595-9. PMID: 18173042
- Elevated Level of Serum Carcinoembryonic Antigen (CEA) and Search for a Malignancy: A Case Report. | Asad-Ur-Rahman, F. and Saif, MW. 2016. Cureus. 8: e648. PMID: 27446768
- Nanopore-based Strategy for Selective Detection of Single Carcinoembryonic Antigen (CEA) Molecules. | Tang, H., et al. 2020. Anal Chem. 92: 3042-3049. PMID: 31970978
- A novel sandwich-type SERS immunosensor for selective and sensitive carcinoembryonic antigen (CEA) detection. | Medetalibeyoglu, H., et al. 2020. Anal Chim Acta. 1139: 100-110. PMID: 33190692
- Carcinoembryonic antigen (CEA) in gallbladder bile and mucosa in cholecystolithiasis. | Akiyama, H., et al. 1986. Acta Chir Scand. 152: 509-13. PMID: 3788394
- Carcinoembryonic antigen (CEA) expression and heterogeneity in primary and autologous metastatic gastric tumours demonstrated by a monoclonal antibody. | Hockey, MS., et al. 1984. Br J Cancer. 49: 129-33. PMID: 6365131
- Carcinoembryonic antigen (CEA) in human colorectal cancers growing subcutaneously in nude mice. | Fiebig, HH. and von Kleist, S. 1983. J Cancer Res Clin Oncol. 105: 238-42. PMID: 6853586
- An enzyme immunoassay for carcinoembryonic antigen (CEA) with homogeneous reactivity to different CEA preparations and low cross-reactivity with CEA-related normal antigens. | Nagasaki, H., et al. 1993. J Immunol Methods. 162: 235-45. PMID: 7686200
- Expression of carcinoembryonic antigen (CEA) and nonspecific crossreacting antigen (NCA) in gastrointestinal cancer; the correlation with degree of differentiation. | Kodera, Y., et al. 1993. Br J Cancer. 68: 130-6. PMID: 8318403
- Carcinoembryonic antigen (CEA) in colonic inflammatory-regenerative and dysplastic epithelial lesions. | Radović, S., et al. 1998. Croat Med J. 39: 15-8. PMID: 9475801
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
pan CEA Antibody (4/3/17) | sc-53824 | 200 µg/ml | $322.00 |