Palmitoyl Aminoethyl Methanethiosulfonate (CAS 1076199-30-8)

Palmitoyl Aminoethyl Methanethiosulfonate (CAS: 1076199-30-8) is a chemical compound characterized by a palmitoyl group linked to an aminoethyl methanethiosulfonate moiety. This molecule is particularly intriguing for its functional group, methanethiosulfonate, which is known for its ability to form disulfide bonds with thiol groups under specific conditions. This reactivity makes it a valuable tool in biochemical research, particularly in the study of protein-lipid interactions and the modification of cysteine residues within proteins. The palmitoyl group, a long-chain fatty acid, aids in anchoring this compound within lipid bilayers or micelles, making it ideal for experiments involving membrane proteins or lipid environments. Researchers utilize Palmitoyl Aminoethyl Methanethiosulfonate to selectively label cysteine residues in proteins, enabling the study of protein structure, function, and dynamics through techniques such as mass spectrometry and fluorescence spectroscopy. This compound′s ability to integrate into lipid layers and react with protein thiols without perturbing the native protein structure is crucial for understanding how proteins interact with lipid membranes, providing insights into fundamental cellular processes such as signal transduction and transport mechanisms across membranes.