Molecular structure of Palmatine chloride, CAS Number: 10605-02-4
Palmatine chloride (CAS 10605-02-4)
See product citations (2)
Alternate Names:
5,6-Dihydro-2,3,9,10-tetramethoxydibenzo[a,g]quinolizinium chloride
Application:
Palmatine chloride is a protoberberine alkaloid and an inhibitor of dopamine generation which reduces Ca2+ levels
CAS Number:
10605-02-4
Purity:
≥96%
Molecular Weight:
387.86
Molecular Formula:
C21H22NO4•Cl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Palmatine chloride hydrate functions as a compound that interacts with DNA and RNA, inhibiting their synthesis and leading to the disruption of cellular processes. It acts as an antimicrobial agent, disrupting the cell membrane of microorganisms and leading to their death. Palmatine chloride hydrate may inhibit the activity of certain enzymes, affecting the metabolism of cells. Its mechanism of action involves binding to specific targets within the cell, interfering with their normal function and ultimately leading to cellular dysfunction. Palmatine Chloride Hydrate has been studied for its potential to affect the growth and proliferation of certain cell types, making it a subject of interest in various research applications. Its mechanism of action involves disrupting cellular processes at the molecular level, making it useful for investigating the fundamental mechanisms of cell biology and biochemistry.
Palmatine chloride (CAS 10605-02-4) References
- Antiphotooxidative activity of protoberberines derived from Coptis japonica makino in the chlorophyll-sensitized photooxidation of oil. | Kim, JP., et al. 2000. J Agric Food Chem. 48: 1058-63. PMID: 10775349
- Sheathless capillary electrophoresis/electrospray mass spectrometry using a carbon-coated tapered fused-silica capillary with a beveled edge. | Chang, YZ., et al. 2001. Anal Chem. 73: 5083-7. PMID: 11721903
- Synthesis and cytotoxicity evaluation of 13-n-alkyl berberine and palmatine analogues as anticancer agents. | Zhang, L., et al. 2012. Molecules. 17: 11294-302. PMID: 23011273
- Development of a method using high-performance liquid chromatographic fingerprint and multi-ingredients quantitative analysis for the quality control of Yangxinshi Pian. | Li, Y., et al. 2015. J Sep Sci. 38: 2989-94. PMID: 26110501
- A robust screening method for dietary agents that activate tumour-suppressor microRNAs. | Hagiwara, K., et al. 2015. Sci Rep. 5: 14697. PMID: 26423775
- Determination of Alkaloid Contents in Various Tissues of Coptis Chinensis Franch. by Reversed Phase-High Performance Liquid Chromatography and Ultraviolet Spectrophotometry. | Yang, Y., et al. 2017. J Chromatogr Sci. 55: 556-563. PMID: 28203760
- [Regional characteristic analysis of alkaloids and chlorogenic acid in wild Phellodendri Amurensis Cortex]. | Zhang, Y., et al. 2016. Zhongguo Zhong Yao Za Zhi. 41: 1797-1802. PMID: 28895323
- Integrating in vitro and in silico approaches to evaluate the 'dual functionality' of palmatine chloride in inhibiting and disassembling Tau-derived VQIVYK peptide fibrils. | Haj, E., et al. 2018. Biochim Biophys Acta Gen Subj. 1862: 1565-1575. PMID: 29634991
- Screening of a library of traditional Chinese medicines to identify anti-malarial compounds and extracts. | Nonaka, M., et al. 2018. Malar J. 17: 244. PMID: 29941026
- Comparative Therapeutic Effects of Natural Compounds Against Saprolegnia spp. (Oomycota) and Amyloodinium ocellatum (Dinophyceae). | Tedesco, P., et al. 2020. Front Vet Sci. 7: 83. PMID: 32154278
- [Review of chemical constituents, pharmacological effects and clinical applications of Jiaotai Pills and predictive analysis of its quality marker(Q-marker)]. | Sun, Y., et al. 2020. Zhongguo Zhong Yao Za Zhi. 45: 2784-2791. PMID: 32627451
- Qingchang Wenzhong Decoction Alleviates DSS-Induced Inflammatory Bowel Disease by Inhibiting M1 Macrophage Polarization In Vitro and In Vivo. | Lu, Q., et al. 2022. Biomed Res Int. 2022: 9427076. PMID: 36060126
- Discovery of New Microbial Collagenase Inhibitors. | Nitulescu, G., et al. 2022. Life (Basel). 12: PMID: 36556479
- Multi-Omics Analysis Reveals the Resistance Mechanism and the Pathogens Causing Root Rot of Coptis chinensis. | Song, X., et al. 2023. Microbiol Spectr. 11: e0480322. PMID: 36809123
- Anti-Trypanosoma cruzi activity of Coptis rhizome extract and its constituents. | Tayama, Y., et al. 2023. Trop Med Health. 51: 12. PMID: 36859380
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Palmatine chloride, 1 g | sc-205788 | 1 g | $80.00 | |||
Palmatine chloride, 5 g | sc-205788A | 5 g | $193.00 |