p39 Antibody (D-9): sc-374030
- p39 Antibody (D-9) is a mouse monoclonal IgG2a κ provided at 200 µg/ml
- raised against amino acids 6-75 mapping near the N-terminus of p39 of human origin
- recommended for detection of p39 of mouse, rat and human origin by WB, IP, IF and ELISA
- m-IgG2a BP-HRP is the preferred secondary detection reagent for p39 Antibody (D-9) for WB applications. This reagent is now offered in a bundle with p39 Antibody (D-9) (see ordering information below).
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SEE ALSO...
p39 Antibody (D-9) is a mouse monoclonal IgG2a antibody that detects p39 in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). p39, a 367-amino acid protein encoded by the human p39 gene located on chromosome 2q35, plays a crucial role in the regulation of the actin cytoskeleton, particularly in neuronal cells. p39 (D-9) antibody localizes to lamellipodial and filopodial structures, as well as growth cones of neurons, indicating involvement in cellular motility and morphology. The interaction of p39 with actin suggests essential functions for maintaining cytoskeleton dynamics, which is vital for processes such as cell migration, synaptic plasticity, and overall neuronal development. Furthermore, p39 expression exhibits a region-specific and developmental stage-specific pattern during embryonic rat brain development, implying distinct roles at different stages of neuronal maturation. The p39/cdk5 kinase complex′s localization at synaptic junctions further highlights potential significance in synaptic function and signaling, making anti-p39 antibody (D-9) a valuable tool for research in neurobiology and related fields.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p39 Antibody (D-9) | sc-374030 | 200 µg/ml | $322.00 | |||
p39 Antibody (D-9): m-IgG2a BP-HRP Bundle | sc-546052 | 200 µg Ab; 10 µg BP | $361.00 |