Molecular structure of p38 MAP Kinase Inhibitor V, CAS Number: 271576-77-3
p38 MAP Kinase Inhibitor V (CAS 271576-77-3)
Alternate Names:
4-(3-(4-Chlorophenyl)-5-(1-methylpiperidin-4-yl)-1H-pyrazol-4-yl)pyrimidine
Application:
p38 MAP Kinase Inhibitor V is a cell-permeable highly potent ATP-competitive inhibitor of CK1 and p38
CAS Number:
271576-77-3
Purity:
>90%
Molecular Weight:
353.85
Molecular Formula:
C19H20ClN5
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
QUICK LINKS
Ordering Information
Description
Technical Information
Safety Information
SDS & Certificate of Analysis
p38 MAP Kinase Inhibitor V is a cell-permeable trisubstituted pyrazole compound that acts as a highly potent ATP-competitive inhibitor of CK1d and p38a (IC50 = 20 and 40 nM, respectively). Shown to affect p38b, PKA, JNK2, and JNK3 activity (IC50 = 2.3, 10.5, 19.7, and 69.7 µM, respectively) only at much higher concentations and exhibit little effect against a panel of 44 other commonly studied kinases, including p38dg, even at a conentraion of 10 µM or higher. An excellent tool for studying p38-mediated responses in cells in vitro .
Inhibitor of:
casein kinase I delta, p38 alpha, and Ser/Thr Protein Kinase.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p38 MAP Kinase Inhibitor V, 1 mg | sc-204160 | 1 mg | $338.00 |