CDKN1B/Kip1 p27 Antibody (SX18F7): sc-53906
- CDKN1B/Kip1 p27 Antibody (SX18F7) is a mouse monoclonal IgG1 κ, cited in 13 publications, provided at 200 µg/ml
- raised against purified GST-p27 Kip1/Kip1 fusion protein of human origin
- recommended for detection of p27 Kip1 of human origin by WB, IP and IF
- See CDKN1B/Kip1 p27 (F-8): sc-1641 for CDKN1B/Kip1 p27 antibody conjugates, including AC, HRP, FITC, PE, Alexa Fluor® 488, 594, 647, 680 and 790.
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for CDKN1B/Kip1 p27 Antibody (SX18F7). This work is in progress.
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SEE ALSO...
p27 Kip1 Antibody (SX18F7) is a mouse monoclonal IgG1 antibody that detects p27 Kip1 in human samples through applications such as western blotting (WB), immunoprecipitation (IP), and immunofluorescence (IF). p27 Kip1 plays a crucial role in regulating the cell cycle by acting as a negative regulator of G1 progression, which is essential for maintaining proper cellular function and preventing uncontrolled cell division that can lead to cancer. p27 Kip1 is primarily located in the nucleus, where p27 Kip1 binds to cyclin-dependent kinases, particularly Cdk4 and Cdk2, thereby inhibiting their activity and preventing the transition from the G1 phase to the S phase of the cell cycle. The regulation of p27 Kip1 is vital, as p27 Kip1 levels can be influenced by various signaling pathways, including TGFβ, which can induce G1 arrest, highlighting p27 Kip1′s importance in cellular responses to stress and damage. anti-p27 Kip1 antibody (SX18F7) is an invaluable tool for researchers studying cell cycle regulation, cancer biology, and the mechanisms of cellular proliferation.
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
CDKN1B/Kip1 p27 Antibody (SX18F7) | sc-53906 | 200 µg/ml | $322.00 |