Date published: 2025-12-24

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P110 (CAS 2770267-63-3)

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Alternate Names:
P-110; P 110
CAS Number:
2770267-63-3
Molecular Weight:
2411.78
Molecular Formula:
C100H179N45O25
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

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P110 (CAS 2770267-63-3) References

  1. A novel Drp1 inhibitor diminishes aberrant mitochondrial fission and neurotoxicity.  |  Qi, X., et al. 2013. J Cell Sci. 126: 789-802. PMID: 23239023
  2. Inhibition of Drp1 mitochondrial translocation provides neural protection in dopaminergic system in a Parkinson's disease model induced by MPTP.  |  Filichia, E., et al. 2016. Sci Rep. 6: 32656. PMID: 27619562
  3. Inhibition of Drp1 hyper-activation is protective in animal models of experimental multiple sclerosis.  |  Luo, F., et al. 2017. Exp Neurol. 292: 21-34. PMID: 28238799
  4. Inhibition of Drp1 hyperactivation reduces neuropathology and behavioral deficits in zQ175 knock-in mouse model of Huntington's disease.  |  Zhao, Y., et al. 2018. Biochem Biophys Res Commun. 507: 319-323. PMID: 30449600
  5. Drp1/Fis1 interaction mediates mitochondrial dysfunction in septic cardiomyopathy.  |  Haileselassie, B., et al. 2019. J Mol Cell Cardiol. 130: 160-169. PMID: 30981733
  6. Mitochondrial dysfunction mediated through dynamin-related protein 1 (Drp1) propagates impairment in blood brain barrier in septic encephalopathy.  |  Haileselassie, B., et al. 2020. J Neuroinflammation. 17: 36. PMID: 31987040
  7. Neuropathic Pain: the Dysfunction of Drp1, Mitochondria, and ROS Homeostasis.  |  Dai, CQ., et al. 2020. Neurotox Res. 38: 553-563. PMID: 32696439
  8. Targeting an allosteric site in dynamin-related protein 1 to inhibit Fis1-mediated mitochondrial dysfunction.  |  Rios, L., et al. 2023. Nat Commun. 14: 4356. PMID: 37468472
  9. PIM1 attenuates cisplatin-induced AKI by inhibiting Drp1 activation.  |  Li, Y., et al. 2024. Cell Signal. 113: 110969. PMID: 37967691
  10. Inhibition of Drp1- Fis1 interaction alleviates aberrant mitochondrial fragmentation and acute kidney injury.  |  Song, Z., et al. 2024. Cell Mol Biol Lett. 29: 31. PMID: 38439028

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

P110, 25 mg

sc-507312
25 mg
$435.00