Molecular structure of P1075, CAS Number: 60559-98-0
P1075 (CAS 60559-98-0)
See product citations (1)
Alternate Names:
N-cyano-N'-(1,1-dimethylpropyl)-N''-3-pyridylguanidine
Application:
P1075 is a potent KATP (Kir6) channel opener
CAS Number:
60559-98-0
Purity:
>99%
Molecular Weight:
231.30
Molecular Formula:
C12H17N5
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
Available in US only.
Available in US only.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
P1075 is a potent KATP (Kir6) channel opener (EC50 for relaxation of aorta = 7.5 nM). P1075 binds to SUR2A and SUR2B with high affinity (Kd values are 17 and 3 nM respectively).
P1075 (CAS 60559-98-0) References
1. Higdon, N.R., et al. 1997. J. Pharmacol. Exp. Ther. 280: 255-260.2. Gross, I., et al. 1999. Mol. Pharmacol. 56: 1370-1373.
3. Buckner, S.A., et al. 2000 Eur. J. Pharmacol. 400: 287-295.
4. Ashcroft, F.M., and Gribble, F.M., 2000. Trends Pharmacol Sci. 21: 439-445.
Activator of:
KIR6.1, and KIR6.2.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
P1075, 10 mg | sc-203657 | 10 mg | $209.00 | |||
| US: Only available in the US | ||||||
P1075, 50 mg | sc-203657A | 50 mg | $877.00 | |||
| US: Only available in the US | ||||||