Date published: 2026-5-16

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p-Toluoyl chloride (CAS 874-60-2)

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Alternate Names:
4-Methylbenzoyl chloride
CAS Number:
874-60-2
Purity:
≥99%
Molecular Weight:
154.59
Molecular Formula:
CH3C6H4COCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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p-Toluoyl chloride is a chemical compound that functions as an acylating agent in organic synthesis. It is involved in the process of acylation, where it reacts with nucleophiles such as amines or alcohols to form amides or esters, respectively. The mechanism of action of p-Toluoyl chloride involves the substitution of the chlorine atom with the nucleophile, resulting in the formation of the desired acylated product. P-Toluoyl Chloride plays a role in the modification of organic molecules, allowing for the introduction of specific functional groups at targeted positions. p-Toluoyl chloride serves as a reagent for the synthesis of various organic compounds, contributing to the diversification of chemical structures. Its mechanism of action involves the activation of the carbonyl group, facilitating the acylation reaction to proceed efficiently.


p-Toluoyl chloride (CAS 874-60-2) References

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  7. Regiospecific and highly stereoselective coupling of 6-(substituted-imidazol-1-yl)purines with 2-deoxy-3,5-di-O-(p-toluoyl)-alpha-D-erythro-pentofuranosyl chloride. Sodium-salt glycosylation in binary solvent mixtures: improved synthesis of cladribine.  |  Zhong, M., et al. 2006. J Org Chem. 71: 7773-9. PMID: 16995685
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

p-Toluoyl chloride, 5 g

sc-250635
5 g
$20.00

p-Toluoyl chloride, 100 g

sc-250635A
100 g
$24.00