p-Toluenesulfonyl fluoride (CAS 455-16-3)

Protease inhibitor P-Toluenesulfonyl fluoride (p-TSF) is a highly potent and versatile reagent extensively utilized in the realms of organic and medicinal chemistry. This powerful compound finds widespread application in diverse laboratory experiments encompassing synthesis, purification, and analysis. Notably, it has demonstrated remarkable efficacy in synthesizing and purifying a wide array of organic compounds. Its significance extends to scientific research applications, where it has been instrumental in various domains. For instance, it contributes to the synthesis and purification of organic compounds, proteins, peptides, and other biomolecules. Additionally, it finds application in synthesizing polymers, surfactants, and a variety of materials. One of the notable attributes of P-Toluenesulfonyl fluoride is its capacity to catalyze a diverse range of chemical reactions. It acts as a nucleophilic reagent, effectively attacking the electrophilic center of a molecule, thus forming a new covalent bond. In this process, a proton from the protonated toluene molecule facilitates the reaction. Importantly, the reaction is reversible, allowing it to be reversed by the addition of a base when required.