p-Ser/Phosphoserine Antibody (4A9): sc-81517
- p-Ser/Phosphoserine Antibody (4A9) is a mouse monoclonal IgM, cited in 1 publications, provided at 50 µg/0.5 ml
- raised against phosphoserine
- recommended for detection of a broad range of serine-phosphorylated proteins in crude cell extracts, preferring positively charged amino acids directly neighbored to phosphoserine of mouse, rat, human and canine origin by WB and IP
- At present, we have not yet completed the identification of the preferred secondary detection reagent(s) for p-Ser/Phosphoserine Antibody (4A9). This work is in progress.
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p-Ser Antibody (4A9) is a mouse monoclonal IgM antibody that detects phosphoserine in mouse, rat, human, and canine samples through applications such as western blotting (WB) and immunoprecipitation (IP). p-Ser (4A9) antibody specifically recognizes phosphorylated serine residues, which play a crucial role in regulating various cellular functions by modulating protein interactions and activities. Phosphorylation of serine residues is a key post-translational modification that can induce significant conformational changes in proteins, thereby influencing enzymatic activity and ability to interact with other proteins. This modification is essential for proper functioning of numerous signaling pathways, as phosphorylation can activate or deactivate proteins involved in critical processes such as cell growth, differentiation, and apoptosis. Anti-p-Ser antibody (4A9) helps researchers effectively characterize proteins with phosphorylated serine residues and gain insights into intricate cellular pathways governed by serine phosphorylation, ultimately advancing understanding of cellular signaling mechanisms and their implications in health and disease.
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p-Ser/Phosphoserine Antibody (4A9) References:
- Mutations responsible for 3-phosphoserine phosphatase deficiency. | Veiga-da-Cunha, M., et al. 2004. Eur J Hum Genet. 12: 163-6. PMID: 14673469
- Phosphoserine-modified calcium phosphate cements: bioresorption and substitution. | Offer, L., et al. 2011. J Tissue Eng Regen Med. 5: 11-9. PMID: 20603870
- Biochemical characterization of phosphoserine phosphatase SerB2 from Mycobacterium marinum. | Pierson, E. and Wouters, J. 2020. Biochem Biophys Res Commun. 530: 739-744. PMID: 32782143
- Neuroprotective role of phosphoserine in primary open-angle glaucoma patients. | Scalinci, SZ., et al. 2020. Eur Rev Med Pharmacol Sci. 24: 9780-9786. PMID: 33090380
- Phosphoserine phosphatase as a prognostic biomarker in patients with gastric cancer and its potential association with immune cells. | Huang, MY., et al. 2022. BMC Gastroenterol. 22: 1. PMID: 34979926
- Phosphoserine phosphatase as an indicator for survival through potentially influencing the infiltration levels of immune cells in neuroblastoma. | Zeng, L., et al. 2022. Front Cell Dev Biol. 10: 873710. PMID: 36092735
- The Phosphoserine Phosphatase Alters the Free Amino Acid Compositions and Fecundity in Cyrtorhinus lividipennis Reuter. | Ahmad, S., et al. 2022. Int J Mol Sci. 23: PMID: 36499611
- Phosphoserine for the generation of lanthanide-binding sites on proteins for paramagnetic nuclear magnetic resonance spectroscopy. | Mekkattu Tharayil, S., et al. 2021. Magn Reson (Gott). 2: 1-13. PMID: 37904776
- In situ grown magnetic COF@MOF with a phosphoserine anchor for in-depth N-glycopeptide analysis in serum. | Guo, Y., et al. 2023. Analyst. 148: 5864-5872. PMID: 37906056
- Multi-objective property optimisation of a phosphoserine-modified calcium phosphate cement for orthopaedic and dental applications using design of experiments methodology. | Tzagiollari, A., et al. 2024. Acta Biomater. 174: 447-462. PMID: 38000527
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
p-Ser/Phosphoserine Antibody (4A9) | sc-81517 | 50 µg/0.5 ml | $322.00 |