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p-Nitrophenyl-β-D-glucuronide (CAS 10344-94-2)

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Alternate Names:
PNPG
Application:
p-Nitrophenyl-β-D-glucuronide is a chromogenic substrate
CAS Number:
10344-94-2
Molecular Weight:
315.2
Molecular Formula:
C12H13NO9
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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p-Nitrophenyl-β-D-glucuronide, also known as 4-Nitrophenyl beta-D-glucopyranosiduronic acid (4-NPB-D-GlcA), is a versatile organic compound that is derived from 4-nitrophenol (4-NP) and glucopyranosiduronic acid. 4-NP has been widely used in various applications such as a dye, preservative, and reagent in organic synthesis. p-Nitrophenyl-β-D-glucuronide has been used as a substrate for the enzyme β-glucosidase in the hydrolysis of glycosidic bonds in both biochemistry and biotechnology.


p-Nitrophenyl-β-D-glucuronide (CAS 10344-94-2) References

  1. The MRP4/ABCC4 gene encodes a novel apical organic anion transporter in human kidney proximal tubules: putative efflux pump for urinary cAMP and cGMP.  |  van Aubel, RAMH., et al. 2002. J Am Soc Nephrol. 13: 595-603. PMID: 11856762
  2. METABOLISM OF DRUGS. 43. COMPARISON OF GLUCURONYL TRANSFER ACTIVITY BETWEEN BETA-GLUCURONIDASE AND URIDINE DIPHOSPHATE TRANSGLUCURONYLASE.  |  TSUKAMOTO, H., et al. 1964. Chem Pharm Bull (Tokyo). 12: 734-7. PMID: 14199173
  3. Identification of salt stress inducible genes that control cell envelope related functions in Azospirillum brasilense Sp7.  |  Nagarajan, T., et al. 2007. Mol Genet Genomics. 278: 43-51. PMID: 17340145
  4. Extraction, partial characterization, and storage stability of β-glucosidase from propolis.  |  Zhang, CP., et al. 2011. J Food Sci. 76: C75-9. PMID: 21535657
  5. Hydrolysis of the soluble fluorescent molecule carboxyumbelliferyl-beta-D-glucuronide by E. coli beta-glucuronidase as applied in a rugged, in situ optical sensor.  |  Geary, JR., et al. 2011. Enzyme Microb Technol. 49: 6-10. PMID: 22112264
  6. Synthesis and application of resorufin β-D-glucuronide, a low-cost chromogenic substrate for detecting Escherichia coli in drinking water.  |  Magro, G., et al. 2014. Environ Sci Technol. 48: 9624-31. PMID: 25035967
  7. Bioprospecting metagenomics of a microbial community on cotton degradation: Mining for new glycoside hydrolases.  |  Zhang, G., et al. 2016. J Biotechnol. 234: 35-42. PMID: 27460447
  8. Purification, biochemical and biophysical characterization of lysosomal β-D-glucuronidase from an edible freshwater mussel, Lamellidens corrianus.  |  Konada, RSR., et al. 2020. Int J Biol Macromol. 152: 465-472. PMID: 32084490
  9. Functional characterization of a novel GH94 glycoside phosphorylase, 3-O-β-d-glucopyranosyl β-d-glucuronide phosphorylase, and implication of the metabolic pathway of acidic carbohydrates in Paenibacillus borealis.  |  Isono, N., et al. 2022. Biochem Biophys Res Commun. 625: 60-65. PMID: 35947916
  10. Alterations in rat liver microsomal and lysosomal -glucuronidase by compounds which induce hepatic drug metabolizing enzymes.  |  Lucier, GW. and McDaniel, OS. 1972. Biochim Biophys Acta. 261: 168-76. PMID: 5012463
  11. Characterization of beta-glucosidase and beta-glucuronidase of alkalotolerant intestinal bacteria.  |  Kim, DH., et al. 1994. Biol Pharm Bull. 17: 423-6. PMID: 8019510
  12. A monoclonal anticarbohydrate antibody detecting superfast myosin in the masseter muscle.  |  Kirkeby, S. 1996. Cell Tissue Res. 283: 85-92. PMID: 8581962
  13. Interference by carbohydrate substrates, flavonoids, and monosaccharide derivatives on bacterial beta-D-glucuronidase assays.  |  Mariscal, A., et al. 1998. Arch Environ Contam Toxicol. 35: 588-93. PMID: 9776776

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

p-Nitrophenyl-β-D-glucuronide, 500 mg

sc-286631
500 mg
$250.00

p-Nitrophenyl-β-D-glucuronide, 1 g

sc-286631A
1 g
$375.00

p-Nitrophenyl-β-D-glucuronide, 5 g

sc-286631B
5 g
$515.00

p-Nitrophenyl-β-D-glucuronide, 10 g

sc-286631C
10 g
$925.00