Date published: 2025-12-4

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p-Anisidine (CAS 104-94-9)

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Alternate Names:
4-Aminoanisole; 4-Methoxyaniline
Application:
p-Anisidine is an aromatic compound used in the detection of aldehydes or ketones in oils
CAS Number:
104-94-9
Molecular Weight:
123.15
Molecular Formula:
C7H9NO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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p-Anisidine functions as a reagent in various research and development applications. It acts as a precursor in the synthesis of dyes and other organic compounds. Its mechanism of action involves participating in nucleophilic aromatic substitution reactions, where it undergoes substitution with other molecules to form new compounds. P-Anisidine may play a role in the modification of organic molecules, contributing to the creation of diverse chemical structures for experimental purposes. At the molecular level, p-Anisidine interacts with other compounds to facilitate the formation of new chemical entities, allowing for the exploration of different chemical properties and behaviors. Its involvement in chemical reactions enables the generation of novel compounds for further study and analysis within experimental applications.


p-Anisidine (CAS 104-94-9) References

  1. Generation of chirality by the aggregation of column structures for two-component molecular crystals composed of chloronitrobenzoic acids and p-anisidine.  |  Sugiyama, T., et al. 2002. Enantiomer. 7: 397-404. PMID: 12643317
  2. cDNA microarray gene expression profiling of hydroxyurea, paclitaxel, and p-anisidine, genotoxic compounds with differing tumorigenicity results.  |  Lee, M., et al. 2003. Environ Mol Mutagen. 42: 91-7. PMID: 12929121
  3. Olive oil stability under deep-frying conditions.  |  Casal, S., et al. 2010. Food Chem Toxicol. 48: 2972-9. PMID: 20678538
  4. Hydrogen bonding in cyclic imides and amide carboxylic acid derivatives from the facile reaction of cis-cyclohexane-1,2-carboxylic anhydride with o- and p-anisidine and m- and p-aminobenzoic acids.  |  Smith, G. and Wermuth, UD. 2012. Acta Crystallogr C. 68: o327-31. PMID: 22935496
  5. Efficient catalysts for asymmetric Mannich reactions.  |  Rachwalski, M., et al. 2013. Org Biomol Chem. 11: 4207-13. PMID: 23685888
  6. Results of the International Validation of the in vivo rodent alkaline comet assay for the detection of genotoxic carcinogens: Individual data for 1,2-dibromoethane, p-anisidine, and o-anthranilic acid in the 2nd step of the 4th phase Validation Study under the JaCVAM initiative.  |  Takasawa, H., et al. 2015. Mutat Res Genet Toxicol Environ Mutagen. 786-788: 144-50. PMID: 26212305
  7. Valorization of soursop flowers (Annona muricata L.) as potent source of natural antioxidants for stabilization of palm olein during accelerated storage.  |  Womeni, HM., et al. 2016. Food Sci Nutr. 4: 802-810. PMID: 27826429
  8. Hepatic co-cultures in vitro reveal suitable to detect Nrf2-mediated oxidative stress responses on the bladder carcinogen o-anisidine.  |  Wewering, F., et al. 2017. Toxicol In Vitro. 40: 153-160. PMID: 28089782
  9. [Determination of p-Anisidine in workplace air by HPLC].  |  Jiang, KY., et al. 2018. Zhonghua Lao Dong Wei Sheng Zhi Ye Bing Za Zhi. 36: 468-471. PMID: 30248753
  10. Oxidation of fish oil supplements in Australia.  |  Heller, M., et al. 2019. Int J Food Sci Nutr. 70: 540-550. PMID: 30626234
  11. Fingerprint-based similarity search identified p-anisidine as an anticancer agent in HeLa and a prospective phytochemical ETV1 transcription factor inhibitor.  |  Nath, A. and Nair, AS. 2021. J Biomol Struct Dyn. 39: 4973-4980. PMID: 32580654
  12. Oxidative stability of direct-expanded chickpea-sorghum snacks.  |  Bekele, EK., et al. 2020. Food Sci Nutr. 8: 4340-4351. PMID: 32884714
  13. The occurrence of 3-monochloropropane-1,2-diol esters and glycidyl esters in vegetable oils during frying.  |  Ahmad Tarmizi, AH. and Kuntom, A. 2022. Crit Rev Food Sci Nutr. 62: 3403-3419. PMID: 33397128

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

p-Anisidine, 5 g

sc-236267
5 g
$27.00

p-Anisidine, 100 g

sc-236267A
100 g
$31.00