Date published: 2026-5-5

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p-Aminoclonidine (CAS 73217-88-6)

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CAS Number:
73217-88-6
Molecular Weight:
281.57
Molecular Formula:
C9H10Cl2N4•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Adrenergic receptor (alpha 2) agonist


p-Aminoclonidine (CAS 73217-88-6) References

  1. Neurotransmitters of the sympathetic nerve terminal are powerful chemoattractants for monocytes.  |  Straub, RH., et al. 2000. J Leukoc Biol. 67: 553-8. PMID: 10770289
  2. Neuropeptide Y cotransmission with norepinephrine in the sympathetic nerve-macrophage interplay.  |  Straub, RH., et al. 2000. J Neurochem. 75: 2464-71. PMID: 11080198
  3. Effects of antisense to the (alpha)2A-adrenoceptors administered into the region of the locus ceruleus on behaviors in plus-maze and sexual behavior tests in sham-operated and castrated male rats.  |  Shishkina, GT., et al. 2001. J Neurosci. 21: 726-31. PMID: 11160451
  4. Differential effects of alpha-adrenoceptor agonists on human retinal microvessel diameter.  |  Spada, CS., et al. 2001. J Ocul Pharmacol Ther. 17: 255-77. PMID: 11436946
  5. Corneal and conjunctival/scleral penetration of p-aminoclonidine, AGN 190342, and clonidine in rabbit eyes.  |  Chien, DS., et al. 1990. Curr Eye Res. 9: 1051-9. PMID: 1982760
  6. Dual regulation of adenylate cyclase and guanylate cyclase: alpha 2-adrenergic signal transduction in adrenocortical carcinoma cells.  |  Jaiswal, N. and Sharma, RK. 1986. Arch Biochem Biophys. 249: 616-9. PMID: 2875690
  7. Antagonist like action of synthetic alpha 2-adrenoceptor agonists on contractile response to catecholamines in smooth muscle strips isolated from rainbow trout stomach (Salmo gairdneri).  |  Kitazawa, T., et al. 1988. Comp Biochem Physiol C Comp Pharmacol Toxicol. 91: 585-8. PMID: 2905974
  8. Clonidine-specific antisera recognize an endogenous clonidine-displacing substance in brain.  |  Meeley, MP., et al. 1989. Hypertension. 13: 341-51. PMID: 2925235
  9. Interaction of clonidine and clonidine analogs with human platelet alpha 2-adrenergic receptors.  |  Steer, ML. and Atlas, D. 1982. Biochim Biophys Acta. 714: 389-94. PMID: 6120721
  10. Enterocyte alpha 2-adrenergic receptors: yohimbine and p-aminoclonidine binding relative to ion transport.  |  Chang, EB., et al. 1983. Am J Physiol. 244: G76-82. PMID: 6295186
  11. [3H]p-aminoclonidine and [3H]idazoxan label different populations of imidazoline sites on rat kidney.  |  MacKinnon, AC., et al. 1993. Eur J Pharmacol. 232: 79-87. PMID: 8096190
  12. Amino acid substitutions at position 312 in the seventh hydrophobic segment of the beta 2-adrenergic receptor modify ligand-binding specificity.  |  Suryanarayana, S. and Kobilka, BK. 1993. Mol Pharmacol. 44: 111-4. PMID: 8101966
  13. Neuronal regulation of interleukin 6 secretion in murine spleen: adrenergic and opioidergic control.  |  Straub, RH., et al. 1997. J Neurochem. 68: 1633-9. PMID: 9084435
  14. A proposed mechanism for p-aminoclonidine allergenicity based on its relative oxidative lability.  |  Thompson, CD., et al. 1997. Chem Res Toxicol. 10: 1032-6. PMID: 9305586

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

p-Aminoclonidine, 1 mg

sc-296001
1 mg
$136.00

p-Aminoclonidine, 5 mg

sc-296001A
5 mg
$444.00