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p-Aminobenzoic acid, Free Acid (CAS 150-13-0)

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Alternate Names:
PABA; Vitamin Bx; Vitamin H1
CAS Number:
150-13-0
Purity:
≥99%
Molecular Weight:
137.14
Molecular Formula:
C7H7NO2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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p-Aminobenzoic acid, Free Acid is a compound of significant interest in the field of organic chemistry, especially for its utility as a building block in the synthesis of various dyes, pigments, and pharmaceuticals. In research, it is employed to study the properties of aromatic amines, including their reactivity in electrophilic substitution reactions. The compound′s carboxylic acid group allows for its participation in amide bond formation, making it a key reactant in peptide synthesis studies. Additionally, p-Aminobenzoic acid, Free Acid is used in polymer research, where it can be incorporated into polymer chains to modify the physical and optical properties of the materials. In the realm of analytical chemistry, this compound serves as a standard for calibrating instruments that measure UV absorption due to its characteristic absorbance properties. It is also used to investigate the kinetics of decarboxylation reactions and the stability of aromatic amine functionalities in various chemical environments.


p-Aminobenzoic acid, Free Acid (CAS 150-13-0) References

  1. Metabolism of sulfadimidine, sulfanilamide, p-aminobenzoic acid, and isoniazid in suspensions of parenchymal and nonparenchymal rat liver cells.  |  Morland, J. and Olsen, H. 1977. Drug Metab Dispos. 5: 511-7. PMID: 21775
  2. Kinetics of the oxidation of p-aminobenzoic acid catalyzed by horseradish peroxidase compounds I and II.  |  Dunford, HB. and Cotton, ML. 1975. J Biol Chem. 250: 2920-32. PMID: 235530
  3. Decrease of ultraviolet-induced DNA injury in human skin by p-aminobenzoic acid esters.  |  De Rijcke, S. and Heenen, M. 1989. Dermatologica. 179: 196-9. PMID: 2620751
  4. Degradation of sunscreen agent p-aminobenzoic acid using a combination system of UV irradiation, persulphate and iron(II).  |  Xue, Y., et al. 2016. Environ Sci Pollut Res Int. 23: 4561-8. PMID: 26517998
  5. Molecular Antioxidant Properties and In Vitro Cell Toxicity of the p-Aminobenzoic Acid (PABA) Functionalized Peptide Dendrimers.  |  Sowinska, M., et al. 2019. Biomolecules. 9: PMID: 30841638
  6. Inhibition of metabolic processes by coenzyme-A-sequestering aromatic acids. Prevention by para-chloro- and para-nitrobenzoic acids.  |  Swartzentruber, MS. and Harris, RA. 1987. Biochem Pharmacol. 36: 3147-53. PMID: 3117062
  7. P-Aminobenzoic acid derivatives as inhibitors of the cell-free H2-pteroate synthesizing system of Escherichia coli.  |  Thijssen, HH. 1977. J Med Chem. 20: 233-6. PMID: 319235
  8. P-Aminobenzoic acid derivatives. Mode of action and structure-activity relationships in a cell-free system (Escherichia coli).  |  Seydel, JK. and Butte, W. 1977. J Med Chem. 20: 439-47. PMID: 321779
  9. Folate deficiency in rats fed amino acid diets.  |  Walzem, RL., et al. 1983. J Nutr. 113: 421-9. PMID: 6296342
  10. The oral pancreatic function test with N-benzoyl-L-tyrosyl-p-aminobenzoic acid: acute toxicity and effects of renal function on this test.  |  Lang, C., et al. 1980. J Clin Chem Clin Biochem. 18: 551-5. PMID: 6969287
  11. [Role of p-aminobenzoic acid in levorin biosynthesis].  |  Aleksintseva, OA., et al. 1982. Antibiotiki. 27: 493-5. PMID: 6982677
  12. Understanding allergic reactions to local anesthetics.  |  Eggleston, ST. and Lush, LW. 1996. Ann Pharmacother. 30: 851-7. PMID: 8826570
  13. p-Aminobenzoic acid, but not its metabolite p-acetamidobenzoic acid, inhibits thrombin induced thromboxane formation in human platelets in a non NSAID like manner.  |  Barbieri, B., et al. 1997. Thromb Res. 86: 127-40. PMID: 9175234

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

p-Aminobenzoic acid, Free Acid, 25 g

sc-208143B
25 g
$35.00

p-Aminobenzoic acid, Free Acid, 50 g

sc-208143
50 g
$47.00

p-Aminobenzoic acid, Free Acid, 250 g

sc-208143A
250 g
$127.00