Molecular structure of Oxythiamine chloride hydrochloride, CAS Number: 614-05-1
Oxythiamine chloride hydrochloride (CAS 614-05-1)
See product citations (2)
Alternate Names:
5-(2-Hydroxyethyl)-3-(4-hydroxy-2-methyl-5-pyrimidinylmethyl)-4-methylthiazolium chloride
Application:
Oxythiamine chloride hydrochloride is a chemical that inhibits transketolase
CAS Number:
614-05-1
Purity:
≥95%
Molecular Weight:
338.25
Molecular Formula:
C12H16ClN3O2S•HCl
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Oxythiamine chloride hydrochloride is a chemical that inhibits transketolase. Transketolase is an enzyme that controls the nonoxidative branch of the pentose phosphate pathway. This helps you study anti-metastatic mechanisms, primarily the metalloproteinases. An inhibitor of thiamine-dependent enzymes.
Oxythiamine chloride hydrochloride (CAS 614-05-1) References
- Zinc(II), cadmium(II) and mercury(II) complexes of the vitamin B1 antagonist oxythiamine. | Casas, JS., et al. 2006. J Inorg Biochem. 100: 124-32. PMID: 16337684
- c-MYC-directed NRF2 drives malignant progression of head and neck cancer via glucose-6-phosphate dehydrogenase and transketolase activation. | Tang, YC., et al. 2021. Theranostics. 11: 5232-5247. PMID: 33859744
- Hexokinase 1 cellular localization regulates the metabolic fate of glucose. | De Jesus, A., et al. 2022. Mol Cell. 82: 1261-1277.e9. PMID: 35305311
Inhibitor of:
3-Hydroxybutyrate Dehydrogenase, AASS, CD39L4, Enzyme, FPGS, MAT Iα, MPST, and Transketolase.Activator of:
Tap42.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oxythiamine chloride hydrochloride, 1 g | sc-236265 | 1 g | $40.00 | |||
Oxythiamine chloride hydrochloride, 5 g | sc-236265A | 5 g | $121.00 | |||
Oxythiamine chloride hydrochloride, 25 g | sc-236265B | 25 g | $446.00 |