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Oxprenolol hydrochloride (CAS 6452-73-9)

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Alternate Names:
Oxprenolol hydrochloride also known as 1-[(1-Methylethyl)amino]-3-[2-(2-propen-1-yloxy)phenoxy]-2-propanol Hydrochloride; 1-(Isopropylamino)-2-hydroxy-3-[o-(allyloxy)phenoxy]propane Hydrochloride; Coretal; Laracor; Paritane; Trasacor
Application:
Oxprenolol hydrochloride is a non-selective β-adrenergic antagonist that also displays intrinsic sympathomimetic activity
CAS Number:
6452-73-9
Purity:
≥98%
Molecular Weight:
301.81
Molecular Formula:
C15H23NO3•HCl
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Oxprenolol hydrochloride has been reported to be a non-selective β-AR (β-adrenergic receptor) inhibitor that also displays intrinsic sympathomimetic activity. Oxprenolol hydrochloride also shows the ability to stabilize cellular membranes and reduce plasma renin activity. Additional data suggests that Oxprenolol hydrochloride demonstrates the ability to counteract the suppressive effects of β-agonist on microglial proliferation.


Oxprenolol hydrochloride (CAS 6452-73-9) References

  1. Oxprenolol-loaded bioadhesive microspheres: preparation and in vitro/in vivo characterization.  |  Preda, M. and Leucuta, SE. 2003. J Microencapsul. 20: 777-89. PMID: 14594666
  2. Microdetermination of oxprenolol hydrochloride and metoprolol tartrate with ammonium metavanadate.  |  Ahmad, S., et al. 1987. Talanta. 34: 296-8. PMID: 18964300
  3. Dermatitis caused by epichlorohydrin, oxprenolol hydrochloride and propranolol hydrochloride.  |  Rebandel, P. and Rudzki, E. 1990. Contact Dermatitis. 23: 199. PMID: 2149329
  4. Spectrophotometric determination of oxprenolol hydrochloride as its Fe (III) complex.  |  Radulović, D., et al. 1990. Farmaco. 45: 447-53. PMID: 2400517
  5. Zero-order release formulation of oxprenolol hydrochloride with swelling and erosion control.  |  Devi, KP., et al. 1989. Pharm Res. 6: 313-7. PMID: 2748519
  6. Oxprenolol hydrochloride: pharmacology, pharmacokinetics, adverse effects and clinical efficacy.  |  Russo, ME. and Covinsky, JO. 1983. Pharmacotherapy. 3: 68-81. PMID: 6344036
  7. Oxprenolol hydrochloride: a long-term study of efficacy, safety, and tolerability.  |  Tarpley, EL. 1982. Pharmacotherapy. 2: 281-4. PMID: 6820501
  8. High-performance liquid chromatographic determination of oxprenolol hydrochloride and metoprolol tartrate in tablets and injections.  |  Mehta, AC. 1982. Analyst. 107: 1379-82. PMID: 7181125
  9. Adrenergic agonists suppress the proliferation of microglia through beta 2-adrenergic receptor.  |  Fujita, H., et al. 1998. Neurosci Lett. 242: 37-40. PMID: 9509999
  10. Relative bioavailability of different oral sustained release oxprenolol tablets.  |  Leucuta, SE., et al. 1998. Eur J Drug Metab Pharmacokinet. 23: 178-84. PMID: 9725478

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Oxprenolol hydrochloride, 100 mg

sc-204152
100 mg
$136.00

Oxprenolol hydrochloride, 2.5 g

sc-204152B
2.5 g
$1977.00

Oxprenolol hydrochloride, 10 g

sc-204152C
10 g
$6763.00

Oxprenolol hydrochloride, 50 g

sc-204152D
50 g
$13525.00