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Oxotremorine Sesquifumarate (CAS 17360-35-9)

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Application:
Oxotremorine Sesquifumarate is An M2 and M4 Muscarinic acetylcholine receptor agonist
CAS Number:
17360-35-9
Molecular Weight:
380.4
Molecular Formula:
C12H18N2O•1.5C4H4O4
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Oxotremorine Sesquifumarate is a compound used in neuroscience research due to its action as a muscarinic acetylcholine receptor agonist. It serves as an important tool for investigating cholinergic system functions, which are critical for various cognitive processes including memory and attention. Researchers employ Oxotremorine Sesquifumarate to study the mechanisms of muscarinic receptors, exploring its effects on signal transduction pathways within the central nervous system. This chemical has been instrumental in examining the role of acetylcholine in synaptic plasticity and in the overall modulation of neural circuitry.


Oxotremorine Sesquifumarate (CAS 17360-35-9) References

  1. Enhancement of D1 dopamine receptor-mediated locomotor stimulation in M(4) muscarinic acetylcholine receptor knockout mice.  |  Gomeza, J., et al. 1999. Proc Natl Acad Sci U S A. 96: 10483-8. PMID: 10468635
  2. Investigations of the cholinergic modulation of GABA release in rat thalamus slices.  |  Rowell, PP., et al. 2003. Neuroscience. 116: 447-53. PMID: 12559099
  3. In vivo antimuscarinic actions of the third generation antihistaminergic agent, desloratadine.  |  Howell, G., et al. 2005. BMC Pharmacol. 5: 13. PMID: 16109168
  4. Heterogeneity of muscarinic receptor-mediated Ca2+ responses in cultured urothelial cells from rat.  |  Kullmann, FA., et al. 2008. Am J Physiol Renal Physiol. 294: F971-81. PMID: 18272602
  5. Safety of administration of human butyrylcholinesterase and its conjugates with soman or VX in rats.  |  Genovese, RF., et al. 2010. Basic Clin Pharmacol Toxicol. 106: 428-34. PMID: 20050840
  6. Muscarinic type 2 receptors in the lateral dorsal tegmental area modulate cocaine and food seeking behavior in rats.  |  Shabani, S., et al. 2010. Neuroscience. 170: 559-69. PMID: 20667466
  7. Qualitative differences in the effects of adenosine analogs on the cholinergic systems of rat striatum and hippocampus.  |  Forloni, GL., et al. 1986. Naunyn Schmiedebergs Arch Pharmacol. 334: 86-91. PMID: 3024027
  8. Differential receptor occupancy requirements for muscarinic cholinergic stimulation of inositol lipid hydrolysis in brain and in neuroblastomas.  |  Fisher, SK. and Snider, RM. 1987. Mol Pharmacol. 32: 81-90. PMID: 3600615
  9. Memory enhancement: supra-additive effect of subcutaneous cholinergic drug combinations in mice.  |  Flood, JF., et al. 1985. Psychopharmacology (Berl). 86: 61-7. PMID: 3927367
  10. Drug induced hypothermia in adult and senescent rats.  |  Martin, JR., et al. 1985. Neurobiol Aging. 6: 121-4. PMID: 4022230
  11. Differential response to cholinergic stimulation in psychogenitically selected rat lines.  |  Martin, JR., et al. 1984. Psychopharmacology (Berl). 83: 262-7. PMID: 6433388
  12. Effects of scopolamine, pilocarpine, and oxotremorine on the exploratory behavior of two psychogenetically selected lines of rats in a complex maze.  |  Martin, JR., et al. 1981. Psychopharmacology (Berl). 72: 135-42. PMID: 6782602
  13. Muscarinic and nicotinic influences on masculine sexual behavior in rats: effects of oxotremorine, scopolamine, and nicotine.  |  Retana-Marquez, S., et al. 1993. Pharmacol Biochem Behav. 44: 913-7. PMID: 8469699

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Oxotremorine Sesquifumarate, 100 mg

sc-200170
100 mg
$67.00

Oxotremorine Sesquifumarate, 500 mg

sc-200170A
500 mg
$260.00