Molecular structure of Oxfendazole, CAS Number: 53716-50-0
Oxfendazole (CAS 53716-50-0)
Alternate Names:
Methyl [5-(phenylsulfinyl)-1H-benzimidazol-2-yl]carbamate
Application:
Oxfendazole is an anthelmintic agent and fenbendazole metabolite
CAS Number:
53716-50-0
Purity:
≥98%
Molecular Weight:
315.35
Molecular Formula:
C15H13N3O3S
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Oxfendazole, a benzimidazole derivative, is a potent anthelmintic drug widely employed for the treatment of diverse parasitic infections. With its broad-spectrum activity, it effectively combats nematodes, cestodes, and trematodes. Oxfendazole exhibits a range of notable biochemical and physiological effects. It inhibits parasite growth, curtails their reproductive capacity, and disrupts their energy production. Additionally, oxfendazole demonstrates anti-inflammatory properties, suppresses toxin production, and mitigates the risk of infection.
Oxfendazole (CAS 53716-50-0) References
- Short Communication: In Vitro Efficacy Testing of Praziquantel, Ivermectin, and Oxfendazole against Taenia Solium Cysts. | Cederberg, S., et al. 2012. J Parasitol Res. 2012: 363276. PMID: 21785697
- Pharmacokinetic assessment of the monepantel plus oxfendazole combined administration in dairy cows. | Ballent, M., et al. 2018. J Vet Pharmacol Ther. 41: 292-300. PMID: 29139145
- Pathway of oxfendazole from the host into the worm: Trichuris suis in pigs. | Hansen, TVA., et al. 2017. Int J Parasitol Drugs Drug Resist. 7: 416-424. PMID: 29156431
- Evaluation of oxfendazole in the treatment of zoonotic Onchocerca lupi infection in dogs. | Colella, V., et al. 2018. PLoS Negl Trop Dis. 12: e0006218. PMID: 29377880
- The anthelmintic agent oxfendazole inhibits cell growth in non‑small cell lung cancer by suppressing c‑Src activation. | Xu, D., et al. 2019. Mol Med Rep. 19: 2921-2926. PMID: 30720086
- Pharmacologic interaction between oxfendazole and triclabendazole: In vitro biotransformation and systemic exposure in sheep. | Viviani, P., et al. 2019. Exp Parasitol. 204: 107718. PMID: 31201779
- Oxfendazole mediates macrofilaricidal efficacy against the filarial nematode Litomosoides sigmodontis in vivo and inhibits Onchocerca spec. motility in vitro. | Hübner, MP., et al. 2020. PLoS Negl Trop Dis. 14: e0008427. PMID: 32628671
- Effect of oxfendazole to control Taenia solium cysticercosis in pigs in Punjab state of India. | Megha, GK., et al. 2020. J Parasit Dis. 44: 553-558. PMID: 32801507
- TSOL18 vaccine and oxfendazole for control of Taenia solium cysticercosis in pigs: A field trial in endemic areas of Tanzania. | Kabululu, ML., et al. 2020. PLoS Negl Trop Dis. 14: e0008785. PMID: 33052939
- Control trial of porcine cysticercosis in Uganda using a combination of the TSOL18 vaccination and oxfendazole. | Nsadha, Z., et al. 2021. Infect Dis Poverty. 10: 34. PMID: 33743828
- Exploitation of nanocrystal suspension as an effective oral formulation for oxfendazole. | Sun, Y., et al. 2022. Drug Deliv Transl Res. 12: 1219-1229. PMID: 34148210
- Effects of Ferula asafetida, closantel, albendazole, oxfendazole, and ivermectin against Haemonchus contortus in goats and sheep. | Jabbar, A., et al. 2022. Trop Anim Health Prod. 54: 107. PMID: 35187616
- Oxfendazole induces protein catabolism and gluconeogenesis in experimental neurocysticercosis. | Correia, LTB., et al. 2022. Acta Trop. 234: 106571. PMID: 35752205
- Pharmacokinetics and pharmacokinetic interactions of orally administered oxfendazole and oxyclozanide tablet formulation to sheep. | Ozdemir Kutahya, Z., et al. 2023. J Vet Pharmacol Ther. 46: 34-41. PMID: 36189621
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oxfendazole, 10 g | sc-205782 | 10 g | $166.00 | |||
Oxfendazole, 25 g | sc-205782A | 25 g | $302.00 |