Molecular structure of Oxetan-3-one, CAS Number: 6704-31-0
Oxetan-3-one (CAS 6704-31-0)
CAS Number:
6704-31-0
Purity:
≥98%
Molecular Weight:
72.06
Molecular Formula:
C3H4O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Oxetan-3-one is integral to the creation of complex molecules like amino acids, peptides, and carbohydrates and is utilized in studies that explore enzyme function and molecular interactions. Oxetan-3-one is reactive with numerous chemical groups, including alcohols, amines, and carboxylic acids, leading to the formation of different compounds such as cyclic ketones, lactones, and esters. The reactions involving Oxetan-3-one typically proceed through a cyclic transition state, which is thought to be supported by hydrogen bonding and spatial arrangement of the molecules involved.
Oxetan-3-one (CAS 6704-31-0) References
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- Oxetanes in drug discovery: structural and synthetic insights. | Wuitschik, G., et al. 2010. J Med Chem. 53: 3227-46. PMID: 20349959
- Gold-catalyzed one-step practical synthesis of oxetan-3-ones from readily available propargylic alcohols. | Ye, L., et al. 2010. J Am Chem Soc. 132: 8550-1. PMID: 20521793
- Highly functional group compatible Rh-catalyzed addition of arylboroxines to activated N-tert-butanesulfinyl ketimines. | Jung, HH., et al. 2011. Org Lett. 13: 3912-5. PMID: 21732591
- Oxetanyl peptides: novel peptidomimetic modules for medicinal chemistry. | McLaughlin, M., et al. 2014. Org Lett. 16: 4070-3. PMID: 25068485
- Structurally Divergent Lithium Catalyzed Friedel-Crafts Reactions on Oxetan-3-ols: Synthesis of 3,3-Diaryloxetanes and 2,3-Dihydrobenzofurans. | Croft, RA., et al. 2016. Chemistry. 22: 16271-16276. PMID: 27723135
- Rhodium(i)-catalyzed stereoselective [4+2] cycloaddition of oxetanols with alkynes through C(sp3)-C(sp3) bond cleavage. | Guo, R., et al. 2017. Chem Sci. 8: 3002-3006. PMID: 28451367
- Evaluation of Oxetan-3-ol, Thietan-3-ol, and Derivatives Thereof as Bioisosteres of the Carboxylic Acid Functional Group. | Lassalas, P., et al. 2017. ACS Med Chem Lett. 8: 864-868. PMID: 28835803
- Macrocyclisation of small peptides enabled by oxetane incorporation. | Roesner, S., et al. 2019. Chem Sci. 10: 2465-2472. PMID: 30881675
- Cobalt(III)-Catalyzed Diastereoselective Three-Component C-H Bond Addition to Butadiene and Activated Ketones. | Shen, Z., et al. 2020. Synthesis (Stuttg). 52: 1239-1246. PMID: 32884161
- Chemical Space Exploration of Oxetanes. | Alves, FRS., et al. 2020. Int J Mol Sci. 21: PMID: 33147789
- 3,3-Dinitratooxetane - an important leap towards energetic oxygen-rich monomers and polymers. | Born, M., et al. 2021. Chem Commun (Camb). 57: 2804-2807. PMID: 33599655
- Structure property relationships of N-acylsulfonamides and related bioisosteres. | Francisco, KR., et al. 2021. Eur J Med Chem. 218: 113399. PMID: 33823393
- Synthesis, Characterization, and Antimicrobial Activity Screening of Some Novel 3-(2-(3-(Substituted benzyloxy)oxetan-3-yl)-3-fluorophenoxy)-8-fluoro-2-methylquinoline Derivatives as Potential Antimycobacterial Agents. | Shinde, A., et al. 2022. ACS Omega. 7: 47096-47107. PMID: 36570236
- Synthesis of New Azetidine and Oxetane Amino Acid Derivatives through Aza-Michael Addition of NH-Heterocycles with Methyl 2-(Azetidin- or Oxetan-3-Ylidene)Acetates. | Gudelis, E., et al. 2023. Molecules. 28: PMID: 36770762
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oxetan-3-one, 250 mg | sc-358697 | 250 mg | $29.00 | |||
Oxetan-3-one, 1 g | sc-358697A | 1 g | $43.00 | |||
Oxetan-3-one, 5 g | sc-358697B | 5 g | $73.00 | |||
Oxetan-3-one, 25 g | sc-358697C | 25 g | $255.00 |