Date published: 2025-9-22

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Oxcarbazepine (CAS 28721-07-5)

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Application:
Oxcarbazepine is a sodium channel protein inhibitor
CAS Number:
28721-07-5
Purity:
≥98%
Molecular Weight:
252.27
Molecular Formula:
C15H12N2O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Oxcarbazepine manifests its anticonvulsant properties through distinct mechanisms that contribute to its efficacy. By binding to voltage-gated sodium channels, Oxcarbazepine effectively curtails their activity, leading to a reduction in their function. Furthermore, Oxcarbazepine exerts its influence by binding to and inhibiting the activity of glutamate receptors.


Oxcarbazepine (CAS 28721-07-5) References

  1. Oxcarbazepine in affective and schizoaffective disorders.  |  Dietrich, DE., et al. 2001. Pharmacopsychiatry. 34: 242-50. PMID: 11778145
  2. Oxcarbazepine in the treatment of bipolar disorder: a review.  |  Pratoomsri, W., et al. 2006. Can J Psychiatry. 51: 540-5. PMID: 16933591
  3. Oxcarbazepine in the maintenance treatment of bipolar disorder.  |  Vasudev, A., et al. 2008. Cochrane Database Syst Rev. 2008: CD005171. PMID: 18254071
  4. Oxcarbazepine for refractory epilepsy: systematic review of the literature.  |  Saconato, H., et al. 2009. Sao Paulo Med J. 127: 150-9. PMID: 19820875
  5. Oxcarbazepine versus carbamazepine monotherapy for partial onset seizures.  |  Koch, MW. and Polman, SK. 2009. Cochrane Database Syst Rev. CD006453. PMID: 19821367
  6. Oxcarbazepine-induced myoclonic status epilepticus in juvenile myoclonic epilepsy.  |  Fanella, M., et al. 2013. Epileptic Disord. 15: 181-7. PMID: 23774821
  7. Comparative risk of major congenital malformations with eight different antiepileptic drugs: a prospective cohort study of the EURAP registry.  |  Tomson, T., et al. 2018. Lancet Neurol. 17: 530-538. PMID: 29680205
  8. Carbamazepine-, Oxcarbazepine-, Eslicarbazepine-Associated Movement Disorder: A Literature Review.  |  Rissardo, JP. and Caprara, ALF. 2020. Clin Neuropharmacol. 43: 66-80. PMID: 32384309
  9. Advances in diagnosis, classification, pathophysiology, and management of trigeminal neuralgia.  |  Bendtsen, L., et al. 2020. Lancet Neurol. 19: 784-796. PMID: 32822636
  10. Current role of carbamazepine and oxcarbazepine in the management of epilepsy.  |  Beydoun, A., et al. 2020. Seizure. 83: 251-263. PMID: 33334546
  11. Population pharmacokinetics of oxcarbazepine: a systematic review.  |  Chen, YT., et al. 2021. Expert Rev Clin Pharmacol. 14: 853-864. PMID: 33851561
  12. Adverse fetal and neonatal outcomes following in-utero exposure to oxcarbazepine: A systematic review and meta-analysis.  |  Athar, F., et al. 2022. Br J Clin Pharmacol. 88: 3600-3609. PMID: 35591806
  13. Oxcarbazepine and Hyponatremia.  |  Čiauškaitė, J., et al. 2022. Medicina (Kaunas). 58: PMID: 35629976
  14. The longitudinal effect of oxcarbazepine on thyroid function in children and adolescents with epilepsy.  |  Park, H., et al. 2022. Epilepsia. 63: 3148-3155. PMID: 36073252

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Oxcarbazepine, 10 mg

sc-204826
10 mg
$158.00