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OSM Antibody (E-4): sc-365136

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Datasheets
  • OSM Antibody (E-4) is a mouse monoclonal IgG3 κ, cited in 1 publications, provided at 200 µg/ml
  • specific for an epitope mapping between amino acids 3-25 within the N-terminus of OSM of human origin
  • recommended for detection of OSM of mouse, rat and human origin by WB, IP, IF and ELISA
  • m-IgG3 BP-HRP is the preferred secondary detection reagent for OSM Antibody (E-4) for WB applications. This reagent is now offered in a bundle with OSM Antibody (E-4) (see ordering information below).
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OSM Antibody (E-4) is a mouse monoclonal IgG3 antibody that detects Oncostatin M (OSM) in mouse, rat, and human samples through applications such as western blotting (WB), immunoprecipitation (IP), immunofluorescence (IF), and enzyme-linked immunosorbent assay (ELISA). Anti-OSM antibody (E-4) recognizes OSM, a glycoprotein that plays a crucial role in regulating cell growth and differentiation, particularly in hematopoietic cells. OSM (E-4) antibody targets OSM, which is primarily secreted by activated macrophages and lymphocytes, and shows elevated expression in response to inflammatory stimuli. OSM monoclonal antibody (E-4) identifies OSM, which can inhibit the proliferation of various human tumor cell lines while sparing normal fibroblasts, making OSM a potential target for cancer therapies. OSM (E-4) monoclonal antibody detects OSM, which shares structural homology with other key cytokines such as leukemia inhibitory factor, granulocyte colony-stimulating factor, and interleukin 6, all involved in immune responses and hematopoiesis. High-affinity binding sites for OSM on both normal and tumor cells underscore OSM′s significance in therapeutic applications, potentially facilitating targeted treatments that leverage these unique properties.

For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

OSM Antibody (E-4)

sc-365136
200 µg/ml
$322.00

OSM Antibody (E-4): m-IgG3 BP-HRP Bundle

sc-550419
200 µg Ab; 40 µg BP
$361.00

OSM (E-4) Neutralizing Peptide

sc-365136 P
100 µg/0.5 ml
$69.00

What application is the blocking peptide sc-365136 P appropriate for?

Asked by: TinTin
Thank you for your question. The blocking peptide is intended for use as a negative control, by pre-adsorbing the mouse monoclonal antibody against the antigen. For full protocol details, please contact our Technical Services Department or view our online protocol here: https://www.scbt.com/scbt/resources/protocols/peptide-neutralization
Answered by: Technical Support
Date published: 2017-02-24
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Rated 5 out of 5 by from Produced positive Western blot data of humanProduced positive Western blot data of human full length recombinant OSM. -SCBT QC
Date published: 2013-09-08
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OSM Antibody (E-4) is rated 5.0 out of 5 by 1.
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