Date published: 2025-10-14

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Oryzalin (CAS 19044-88-3)

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CAS Number:
19044-88-3
Purity:
≥95%
Molecular Weight:
346.36
Molecular Formula:
C12H18N4O6S
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Oryzalin, known by various names such as Oryza, Oryzalis, and Oryzal, is a synthetic herbicide extensively employed in crop farming to manage weed growth. Belonging to the dinitroaniline family, this herbicide effectively controls annual grasses, broadleaf weeds, and even certain woody plants. With a remarkable track record of over three decades in agriculture, Oryzalin has gained popularity worldwide for its ability to combat weeds. The mechanism of action of Oryzalin involves hindering cell division in targeted plants, thus ensuring its efficacy against a diverse range of unwanted vegetation.


Oryzalin (CAS 19044-88-3) References

  1. Effect of the antitubulin drug oryzalin on the encystation of Entamoeba invadens.  |  Makioka, A., et al. 2000. Parasitol Res. 86: 625-9. PMID: 10952260
  2. Rapid and Reversible High-Affinity Binding of the Dinitroaniline Herbicide Oryzalin to Tubulin from Zea mays L.  |  Hugdahl, JD. and Morejohn, LC. 1993. Plant Physiol. 102: 725-740. PMID: 12231861
  3. Oryzalin-induced chromosome doubling in Rosa and its effect on plant morphology and pollen viability.  |  Kermani, MJ., et al. 2003. Theor Appl Genet. 107: 1195-200. PMID: 12955205
  4. Surflan and oryzalin impair reproduction in the teleost medaka (Oryzias latipes).  |  Hall, LC., et al. 2007. Mar Environ Res. 63: 115-31. PMID: 16979231
  5. Oryzalin bodies: in addition to its anti-microtubule properties, the dinitroaniline herbicide oryzalin causes nodulation of the endoplasmic reticulum.  |  Langhans, M., et al. 2009. Protoplasma. 236: 73-84. PMID: 19557498
  6. Synthesis and evaluation of oryzalin analogs against Toxoplasma gondii.  |  Endeshaw, MM., et al. 2010. Bioorg Med Chem Lett. 20: 5179-83. PMID: 20675138
  7. Lipid nanoparticles containing oryzalin for the treatment of leishmaniasis.  |  Lopes, R., et al. 2012. Eur J Pharm Sci. 45: 442-50. PMID: 21983568
  8. Oryzalin combined with adventitious regeneration for an efficient chromosome doubling of trihaploid kiwifruit.  |  Chalak, L. and Legave, JM. 1996. Plant Cell Rep. 16: 97-100. PMID: 24178664
  9. Oryzalin, a dinitroaniline herbicide, binds to plant tubulin and inhibits microtubule polymerization in vitro.  |  Morejohn, LC., et al. 1987. Planta. 172: 252-64. PMID: 24225878
  10. Inducing autotetraploids in cassava using oryzalin and colchicine and their in vitro morphophysiological effects.  |  de J da S de Carvalho, M., et al. 2016. Genet Mol Res. 15: PMID: 27420952
  11. Herbicide oryzalin inhibits human carbonic anhydrases in vitro.  |  Baranauskiene, L. and Matulis, D. 2017. J Biochem Mol Toxicol. 31: PMID: 28251759
  12. Unveiling the Possible Oryzalin-Binding Site in the α-Tubulin of Toxoplasma gondii.  |  Aguayo-Ortiz, R. and Dominguez, L. 2022. ACS Omega. 7: 18434-18442. PMID: 35694483
  13. Molecular basis of Toxoplasma gondii oryzalin resistance from a novel α-tubulin binding site model.  |  Flores-León, CD., et al. 2022. Arch Biochem Biophys. 730: 109398. PMID: 36116504
  14. Oryzalin impairs maternal-fetal interaction during early pregnancy via ROS-mediated P38 MAPK/AKT and OXPHOS downregulation.  |  Ham, J., et al. 2023. Food Chem Toxicol. 174: 113665. PMID: 36775140
  15. Inhibition of intracellular Ca2+ signalling, cytotoxicity and antitumor activity of the herbicide oryzalin and its analogues.  |  Powis, G., et al. 1997. Cancer Chemother Pharmacol. 41: 22-8. PMID: 9443610

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Oryzalin, 100 mg

sc-250616
100 mg
$71.00