Date published: 2025-11-1

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Oncrasin 1 (CAS 75629-57-1)

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Alternate Names:
1-[(4-Chlorophenyl)methyl]-1H-indole-3-carboxaldehyde
Application:
Oncrasin 1 is a proapoptotic compound
CAS Number:
75629-57-1
Purity:
>99%
Molecular Weight:
269.73
Molecular Formula:
C16H12CINO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Proapoptotic substance. Induces abnormal nuclear aggregation of PKCι and suppressing RNA transcription. Displays antiproliferative effects against various human tumor cell lines. Shown to inhibit human xenograft growth by 75% in vivo.


Oncrasin 1 (CAS 75629-57-1) References

Guo et al (2007) Identification of a small molecule with synthetic lethality for K-ras and protein kinase C iota. Cancer Res. 68 7403. Guo et al (2009) Interruption of RNA processing machinery by a small compound, 1-[(4-chlorophenyl)methyl]-1H-indole-3-carboxaldehyde (oncrasin-1). Mol.Cancer Ther. 8 441.

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Oncrasin 1, 10 mg

sc-204146
10 mg
$145.00

Oncrasin 1, 50 mg

sc-204146A
50 mg
$615.00