ω-3 Arachidonic Acid-d8

ω-3 Arachidonic Acid-d8 is a deuterated derivative of arachidonic acid, a polyunsaturated ω-6 fatty acid that is a key component in the physiologic regulation of inflammatory processes through eicosanoid production. This particular chemical variant incorporates deuterium atoms, a stable isotope of hydrogen, replacing specific hydrogen atoms in the arachidonic acid molecule. The inclusion of deuterium not only increases the molecular stability but also allows for enhanced tracing and detection in experimental setups, particularly useful in metabolic studies using mass spectrometry or NMR spectroscopy. In research, ω-3 Arachidonic Acid-d8 has been extensively used to investigate lipid metabolism pathways and the biosynthesis of eicosanoids, which are signaling molecules that play significant roles in inflammation and other cellular functions. By utilizing this deuterated compound, scientists are able to track and quantify the enzymatic conversion processes of arachidonic acid into various metabolites with greater accuracy, thus providing clearer insights into the dynamics of lipid signaling networks. The application of ω-3 Arachidonic Acid-d8 in research helps in understanding how modifications in fatty acid substrates can influence the production and action of bioactive lipid mediators at the molecular level.