Date published: 2026-3-26

1-800-457-3801

SCBT Portrait Logo
Seach Input

ω-3 Arachidonic Acid (CAS 24880-40-8)

0.0(0)
Write a reviewAsk a question

See product citations (1)

Alternate Names:
8Z,11Z,14Z,17Z-eicosatetraenoic acid; ω-3 AA
Application:
ω-3 Arachidonic Acid is an inhibitor of arachidonoyl-CoA synthetase
CAS Number:
24880-40-8
Purity:
≥95%
Molecular Weight:
304.5
Molecular Formula:
C20H32O2
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

ω-3 Arachidonic acid, a rare polyunsaturated fatty acid (PUFA). It exhibits a unique interaction within cellular models, particularly through its inhibition of the enzyme arachidonoyl-CoA synthetase, which plays a role in lipid metabolism. The inhibition kinetics of ω-3 arachidonic acid are characterized by a Ki value of 14 µM in human cell cultures, demonstrating its potent bioactive properties. Further studies utilizing calf brain extracts have corroborated its efficacy, where it presents an IC50 value of approximately 5 µM. These findings underscore its potential utility in biochemical research, especially in studies focused on understanding the modulation of lipid enzymatic pathways and the broader implications on cellular lipid composition and function.


ω-3 Arachidonic Acid (CAS 24880-40-8) References

  1. Chemical C2-elongation of polyunsaturated fatty acids.  |  Kuklev, DV. and Smith, WL. 2006. Chem Phys Lipids. 144: 172-7. PMID: 17049508
  2. Gamma-linolenic and stearidonic acids are required for basal immunity in Caenorhabditis elegans through their effects on p38 MAP kinase activity.  |  Nandakumar, M. and Tan, MW. 2008. PLoS Genet. 4: e1000273. PMID: 19023415
  3. Omega-3 fatty acids in health and disease and in growth and development.  |  Simopoulos, AP. 1991. Am J Clin Nutr. 54: 438-63. PMID: 1908631
  4. Brain lipid composition in rabbits after total parenteral nutrition with two different lipid emulsions.  |  Maciá-Botejara, E., et al. 2013. Nutrition. 29: 313-7. PMID: 23237652
  5. Molecular strategies of the Caenorhabditis elegans dauer larva to survive extreme desiccation.  |  Erkut, C., et al. 2013. PLoS One. 8: e82473. PMID: 24324795
  6. Aging. Lysosomal signaling molecules regulate longevity in Caenorhabditis elegans.  |  Folick, A., et al. 2015. Science. 347: 83-6. PMID: 25554789
  7. Endometrium metabolomic profiling reveals potential biomarkers for diagnosis of endometriosis at minimal-mild stages.  |  Li, J., et al. 2018. Reprod Biol Endocrinol. 16: 42. PMID: 29712562
  8. 'Redox lipidomics technology: Looking for a needle in a haystack'.  |  Tyurina, YY., et al. 2019. Chem Phys Lipids. 221: 93-107. PMID: 30928338
  9. Adiponectin receptor PAQR-2 signaling senses low temperature to promote C. elegans longevity by regulating autophagy.  |  Chen, YL., et al. 2019. Nat Commun. 10: 2602. PMID: 31197136
  10. Structural characterization of life-extending Caenorhabditis elegans Lipid Binding Protein 8.  |  Tillman, MC., et al. 2019. Sci Rep. 9: 9966. PMID: 31292465
  11. Alterations in Tissue Metabolite Profiles with Amifostine-Prophylaxed Mice Exposed to Gamma Radiation.  |  Cheema, AK., et al. 2020. Metabolites. 10: PMID: 32455594
  12. Juniperonic Acid Biosynthesis is Essential in Caenorhabditis Elegans Lacking Δ6 Desaturase (fat-3) and Generates New ω-3 Endocannabinoids.  |  Guha, S., et al. 2020. Cells. 9: PMID: 32961767
  13. Physiological and Metabolite Alterations Associated with Neuronal Signals of Caenorhabditis elegans during Cronobacter sakazakii Infections.  |  Muthubharathi, BC., et al. 2021. ACS Chem Neurosci. 12: 4336-4349. PMID: 34704733
  14. Fatty acid structural requirements for activity of arachidonoyl-CoA synthetase.  |  Neufeld, EJ., et al. 1984. J Lipid Res. 25: 288-93. PMID: 6726081

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

ω-3 Arachidonic Acid, 1 mg

sc-229695
1 mg
$191.00

ω-3 Arachidonic Acid, 10 mg

sc-229695A
10 mg
$1609.00