Molecular structure of OMDM-2
OMDM-2
Application:
OMDM-2 is a potent inhibitor of cellular anandamide uptake
Molecular Weight:
431.66
Molecular Formula:
C27H45NO3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
OMDM-2 is a metabolically stable, potent inhibitor of cellular anandamide uptake (neuronal (C6 glioma cells): IC50 = 3.2 µM; non-neuronal (rat RBL-2H3 cells): IC50 = 17 µM) with negligible effects on CB1 receptor (CB1: Ki = 5.1 µM; CB2: Ki > 10 µM), TRPV1 (EC50 = 10 µM) and FAAH (IC50 > 100 µM).
OMDM-2 References
Novel selective and metabolically stable inhibitors of anandamide cellular uptake: G. Ortar, et al.; Biochem. Pharmacol. 65, 1473 (2003) Selective inhibition of anandamide cellular uptake versus enzymatic hydrolysis--a difficult issue to handle: C.J. Fowler, et al.; Eur. J. Pharmacol. 492, 1 (2004) Further evidence for the existence of a specific process for the membrane transport of anandamide: A. Ligresti, et al.; Biochem. J. 380, 265 (2004) In vivo pharmacological actions of two novel inhibitors of anandamide cellular uptake: E. de Lago, et al.; Eur. J. Pharmacol. 484, 249 (2004)Inhibitor of:
FAAH.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
OMDM-2, 5 mg | sc-204145 | 5 mg | $75.00 |