Date published: 2026-2-10

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Oleoyl chloride (CAS 112-77-6)

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Alternate Names:
Oleic Acid Chloride
CAS Number:
112-77-6
Purity:
≥98%
Molecular Weight:
300.91
Molecular Formula:
C18H33ClO
Supplemental Information:
This is classified as a Dangerous Good for transport and may be subject to additional shipping charges.
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Oleoyl chloride, also referred to as oleic acid chloride, is a chemical compound derived from fatty acids. It plays a significant role as an intermediate in organic synthesis and finds wide-ranging applications. Moreover, oleoyl chloride is employed in the production of various lipid-based compounds, including surfactants and emulsifiers. Beyond its role in organic synthesis, oleoyl chloride also contributes to the manufacturing of polymers and coatings. Although the complete mechanism of action of oleoyl chloride remains elusive, it is believed that the reaction between oleic acid and thionyl chloride leads to the formation of oleoyl chloride and hydrogen chloride. Subsequently, hydrogen chloride reacts with oleoyl chloride acid, resulting in the generation of oleoyl chloride.


Oleoyl chloride (CAS 112-77-6) References

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  2. Chemical modification of jute fibers for the production of green-composites.  |  Corrales, F., et al. 2007. J Hazard Mater. 144: 730-5. PMID: 17320283
  3. Effect of the molecular mass and degree of substitution of oleoylchitosan on the structure, rheological properties, and formation of nanoparticles.  |  Li, YY., et al. 2007. J Agric Food Chem. 55: 4842-7. PMID: 17497792
  4. Modification of lysozyme with oleoyl chloride for broadening the antimicrobial specificity.  |  Evran, S., et al. 2010. Prep Biochem Biotechnol. 40: 316-25. PMID: 21108135
  5. Preparation and characterization of nanoparticles based on hydrophobic alginate derivative as carriers for sustained release of vitamin D3.  |  Li, Q., et al. 2011. J Agric Food Chem. 59: 1962-7. PMID: 21288023
  6. Rapid esterification of wheat straw hemicelluloses induced by microwave irradiation.  |  Xu, F., et al. 2008. Carbohydr Polym. 73: 612-20. PMID: 26048228
  7. Total synthesis of a cyclopropane-fatty acid α-glucosyl diglyceride from Lactobacillus plantarum and identification of its ability to signal through Mincle.  |  Shah, S., et al. 2016. Chem Commun (Camb). 52: 10902-5. PMID: 27533919
  8. Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.  |  Preiss, J., et al. 1986. J Biol Chem. 261: 8597-600. PMID: 3013856
  9. Silibinin encapsulation in polymersome: A promising anticancer nanoparticle for inducing apoptosis and decreasing the expression level of miR-125b/miR-182 in human breast cancer cells.  |  Hossainzadeh, S., et al. 2019. J Cell Physiol. 234: 22285-22298. PMID: 31073992
  10. Highly efficient synthesis of 4,4-dimethylsterol oleates using acyl chloride method through esterification.  |  Xie, L., et al. 2021. Food Chem. 364: 130140. PMID: 34175623
  11. Unravelling the Hydration Barrier of Lignin Oleate Nanoparticles for Acid- and Base-Catalyzed Functionalization in Dispersion State.  |  Moreno, A., et al. 2021. Angew Chem Int Ed Engl. 60: 20897-20905. PMID: 34196470
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Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Oleoyl chloride, 250 mg

sc-215625
250 mg
$102.00