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Oleic Acid-13C (CAS 82005-44-5)

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Alternate Names:
Oleic acid-1-13C
Application:
Oleic Acid-13C is a labeled Oleic acid
CAS Number:
82005-44-5
Molecular Weight:
283.45
Molecular Formula:
C17(13C)H34O2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Oleic Acid-13C, assigned CAS number 82005-44-5, is a labeled analog of oleic acid, where the carbon-13 isotope (^13C) has been incorporated into the molecule. This specific modification makes it a valuable tool in various research fields, particularly in studies involving metabolic pathways and lipid biochemistry, where tracking and analysis of lipid utilization and degradation are necessary. Oleic Acid-13C retains the chemical properties of its unlabeled counterpart—a monounsaturated fatty acid primarily found in vegetable oils and animal fats, known for its cis-double bond at the ninth carbon, contributing to its liquid state at room temperature. The incorporation of the ^13C isotope does not alter the biological activity or physical properties of the molecule but enables researchers to use mass spectrometry and NMR spectroscopy to accurately trace the metabolic fate of oleic acid in complex biological systems. This isotopic labeling is crucial for studies focused on lipidomics, where understanding the dynamics of lipid metabolism and its implications on cellular processes is essential. Besides, Oleic Acid-13C has been used in environmental studies to trace organic carbon sources and transformations. This isotopic tool enhances the precision of biochemical studies by providing a non-invasive means to monitor and quantify biological processes, thereby contributing to a deeper understanding of lipid function in various biological and ecological contexts.


Oleic Acid-13C (CAS 82005-44-5) References

  1. Intracisternal administration of transforming growth factor-beta evokes fever through the induction of cyclooxygenase-2 in brain endothelial cells.  |  Matsumura, S., et al. 2008. Am J Physiol Regul Integr Comp Physiol. 294: R266-75. PMID: 17959708
  2. A method for the simultaneous determination of 3T3-L1 adipocyte metabolites by liquid chromatography/mass spectrometry using [(13)C]-stable isotopes.  |  Nagai, H., et al. 2011. Biosci Biotechnol Biochem. 75: 1485-9. PMID: 21821950
  3. Placental fatty acid transfer: a key factor in fetal growth.  |  Larqué, E., et al. 2014. Ann Nutr Metab. 64: 247-53. PMID: 25300267
  4. Metabolism of 13C-Labeled Fatty Acids in Term Human Placental Explants by Liquid Chromatography-Mass Spectrometry.  |  Watkins, OC., et al. 2019. Endocrinology. 160: 1394-1408. PMID: 30920585
  5. In vivo kinetic study of materno-fetal fatty acid transfer in obese and normal weight pregnant women.  |  Gázquez, A., et al. 2019. J Physiol. 597: 4959-4973. PMID: 31287560
  6. Myo-inositol alters 13C-labeled fatty acid metabolism in human placental explants.  |  Watkins, OC., et al. 2019. J Endocrinol.. PMID: 31404911
  7. Cutin Synthesis in Developing, Field-Grown Apple Fruit Examined by External Feeding of Labelled Precursors.  |  Si, Y., et al. 2021. Plants (Basel). 10: PMID: 33807966
  8. Metabolic Patterns of High-Invasive and Low-Invasive Oral Squamous Cell Carcinoma Cells Using Quantitative Metabolomics and 13C-Glucose Tracing.  |  Jiang, W., et al. 2023. Biomolecules. 13: PMID: 38136676
  9. Interactions of the carboxyl group of oleic acid with bovine serum albumin: a 13C NMR study.  |  Parks, JS., et al. 1983. J Biol Chem. 258: 9262-9. PMID: 6874688

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Oleic Acid-13C, 10 mg

sc-212471
10 mg
$150.00

Oleic Acid-13C, 500 mg

sc-212471A
500 mg
$1255.00