Molecular structure of Oleanolic Acid, CAS Number: 508-02-1
Oleanolic Acid (CAS 508-02-1)
See product citations (8)
Alternate Names:
Caryophyllin
Application:
Oleanolic Acid is a compound useful for the induction of iNOS and of Cyclooxygenase 2
CAS Number:
508-02-1
Purity:
≥97%
Molecular Weight:
456.7
Molecular Formula:
C30H48O3
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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SDS & Certificate of Analysis
Oleanolic Acid is a naturally occurring triterpenoid found in garlic and Phytolacca Americana. Exhibits strong anti-HIV activity. Mechanism of action is the induction of iNOS and of Cyclooxygenase 2. Oleanolic Acid is an inhibitor of group II sPLA2.
Oleanolic Acid (CAS 508-02-1) References
- Oleanolic acid and related derivatives as medicinally important compounds. | Sultana, N. and Ata, A. 2008. J Enzyme Inhib Med Chem. 23: 739-56. PMID: 18618318
- Oleanolic acid induces relaxation and calcium-independent release of endothelium-derived nitric oxide. | Rodriguez-Rodriguez, R., et al. 2008. Br J Pharmacol. 155: 535-46. PMID: 18622409
- Oleanolic acid and related triterpenoids from olives on vascular function: molecular mechanisms and therapeutic perspectives. | Rodriguez-Rodriguez, R. 2015. Curr Med Chem. 22: 1414-25. PMID: 25515513
- Oleanolic acid derivatives for pharmaceutical use: a patent review. | Lin, C., et al. 2016. Expert Opin Ther Pat. 26: 643-55. PMID: 27113324
- Oleanolic Acid and Its Derivatives: Biological Activities and Therapeutic Potential in Chronic Diseases. | Ayeleso, TB., et al. 2017. Molecules. 22: PMID: 29137205
- New Applications of Oleanolic Acid and its Derivatives as Cardioprotective Agents: A Review of their Therapeutic Perspectives. | Sun, N., et al. 2019. Curr Pharm Des. 25: 3740-3750. PMID: 31692428
- Prophylactic and therapeutic roles of oleanolic acid and its derivatives in several diseases. | Sen, A. 2020. World J Clin Cases. 8: 1767-1792. PMID: 32518769
- Oleanolic Acid Protects the Skin from Particulate Matter-Induced Aging. | Kim, YJ., et al. 2021. Biomol Ther (Seoul). 29: 220-226. PMID: 32952129
- Development and Evaluation of Oleanolic Acid Dosage Forms and Its Derivatives. | Feng, A., et al. 2020. Biomed Res Int. 2020: 1308749. PMID: 33299854
- Hypotensive Effects of the Triterpene Oleanolic Acid for Cardiovascular Prevention. | Sureda, A., et al. 2021. Curr Mol Pharmacol. 14: 935-942. PMID: 33390142
- Advances on the Anti-Inflammatory Activity of Oleanolic Acid and Derivatives. | Zhang, X., et al. 2021. Mini Rev Med Chem. 21: 2020-2038. PMID: 33573541
- Research Advances in Protective Effects of Ursolic Acid and Oleanolic Acid Against Gastrointestinal Diseases. | Shi, Y., et al. 2021. Am J Chin Med. 49: 413-435. PMID: 33622215
- Oleanolic Acid: Extraction, Characterization and Biological Activity. | Castellano, JM., et al. 2022. Nutrients. 14: PMID: 35276982
- Oleanolic acid and ursolic acid: therapeutic potential in neurodegenerative diseases, neuropsychiatric diseases and other brain disorders. | Chen, C., et al. 2023. Nutr Neurosci. 26: 414-428. PMID: 35311613
- Recent advances in medicinal chemistry of oleanolic acid derivatives. | Yang, YH., et al. 2022. Phytochemistry. 203: 113397. PMID: 36029846
Inhibitor of:
α-Amylase, from pig pancreas, β-glucuronidase, 2210016F16Rik, 4921521F21Rik, AKR7, AMPKα1, Angiogenesis, APOBEC3B, cGKII, colipase, CTAP-III, DHRS7B, EG668526, GD3 Synthase, GPR119, GPT2, group II sPLA2, HAS2, HYAL2, IL-20, IL-TIFb, Keap1, NFKBIL1, nPKC η, PEPCK-C, Pez, PTP 1B, RDH7, Reg IIIβ, SENP3, SLP-76, TMPRSS11C, and V1RF1.Activator of:
20S Proteasome β1, Abcg3, ALDH2, ALDH3A2, ALDH3B2, APPL1, B7-H3, BOULE, BSEP, C030014O09Rik, CAGE, cornulin, CYP2T4, Cyp4f16, cystatin C, D10Wsu102e, D130037M23Rik, DUSP5, EG240327, EG329055, EG432879, EG434396, EG625716, Elastase-3B, FAM84B, FBXW22, Fpr-rs6, Fukutin, Glut1, Glut4, Glut6, Glutamate-Pyruvate Transaminase, GPR172A, ICOS, IL-17RB, IL-1RAcP, IL-27, KRTAP1-5, KRTAP2-1, KRTAP5-2, LCE2C, LMP7, LOXL1, LRIF, MBNL1, MRP7, Nrf2, OTTMUSG00000004968, OTTMUSG00000005723, OTTMUSG00000011270, PKC epsilon, PSPC1, PTP22, PTPRQ, SETX, SHP, SIRT6, SLC22A9, SULT2A4, TGR5, TMPRSS11D, TRIM30C, TRIM35, and ZNF484.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oleanolic Acid, 100 mg | sc-205775 | 100 mg | $86.00 | |||
Oleanolic Acid, 500 mg | sc-205775A | 500 mg | $302.00 |