Molecular structure of Oleamide, CAS Number: 301-02-0
Oleamide (CAS 301-02-0)
Alternate Names:
9,10-Octadecenoamide
Application:
Oleamide is a CB1, 5-HT2A and 2C receptor agonist
CAS Number:
301-02-0
Molecular Weight:
281.48
Molecular Formula:
C18H35NO
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.
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Description
Technical Information
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SDS & Certificate of Analysis
Oleamide is an endogenous lipid. Oleamide acts as an agonist at the CB1 cannabinoid receptor (EC50 = 1.64 muM). Oleamide also appears to potentiate the actions of 5-HT on 5-HT2A and 2C receptors, and act via an allosteric regulatory site on 5-HT7 receptors.
Oleamide (CAS 301-02-0) References
- Allosteric regulation by oleamide of the binding properties of 5-hydroxytryptamine7 receptors. | Hedlund, PB., et al. 1999. Biochem Pharmacol. 58: 1807-13. PMID: 10571256
- Oleamide is a selective endogenous agonist of rat and human CB1 cannabinoid receptors. | Leggett, JD., et al. 2004. Br J Pharmacol. 141: 253-62. PMID: 14707029
- Identification of P2Y receptors involved in oleamide-suppressing inflammatory responses in murine microglia and human dendritic cells. | Kita, M., et al. 2019. Sci Rep. 9: 3135. PMID: 30816271
- Interference of oleamide with analytical and bioassay results. | Jug, U., et al. 2020. Sci Rep. 10: 2163. PMID: 32034225
- Chinese Herbal Medicine (MaZiRenWan) Improves Bowel Movement in Functional Constipation Through Down-Regulating Oleamide. | Huang, T., et al. 2019. Front Pharmacol. 10: 1570. PMID: 32038247
- Effects of Oleamide on the Vasomotor Responses in the Rat. | Hernández-Díaz, C., et al. 2020. Cannabis Cannabinoid Res. 5: 42-50. PMID: 32322675
- Oleamide, a Bioactive Compound, Unwittingly Introduced into the Human Body through Some Plastic Food/Beverages and Medicine Containers. | Naumoska, K., et al. 2020. Foods. 9: PMID: 32369935
- Anti-Biofouling Features of Eco-Friendly Oleamide-PDMS Copolymers. | Seo, E., et al. 2020. ACS Omega. 5: 11515-11521. PMID: 32478240
- Oleamide rescues tibialis anterior muscle atrophy of mice housed in small cages. | Kobayashi, Y., et al. 2021. Br J Nutr. 126: 481-491. PMID: 33143796
- Improving the sensitivity of estimating CBD and other xenobiotics in plasma samples: Oleamide-induced transient matrix effect. | Dawidowicz, AL., et al. 2021. J Pharm Biomed Anal. 204: 114265. PMID: 34298472
- Oleamide as analyte protectant in GC analysis of THC and its metabolites in blood. | Dawidowicz, AL., et al. 2022. J Pharm Biomed Anal. 215: 114800. PMID: 35489245
- Oleamide-Mediated Polarization of M1 Macrophages and IL-1β Production by Regulating NLRP3-Inflammasome Activation in Primary Human Monocyte-Derived Macrophages. | Wisitpongpun, P., et al. 2022. Front Immunol. 13: 856296. PMID: 35514993
- Effective Icephobicity of Silicone Oil-Infused Oleamide-Polydimethylsiloxane with Enhanced Lubrication Lifetime. | Lee, SJ. and Park, GD. 2022. ACS Omega. 7: 21156-21162. PMID: 35755368
- Chemical characterization of a family of brain lipids that induce sleep. | Cravatt, BF., et al. 1995. Science. 268: 1506-9. PMID: 7770779
- Brain lipids that induce sleep are novel modulators of 5-hydroxytrypamine receptors. | Huidobro-Toro, JP. and Harris, RA. 1996. Proc Natl Acad Sci U S A. 93: 8078-82. PMID: 8755606
Inhibitor of:
connexin 31.Activator of:
CB1.Substrate of:
FAAH.Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Oleamide, 10 mg | sc-358696 | 10 mg | $60.00 | |||
Oleamide, 25 mg | sc-358696A | 25 mg | $71.00 | |||
Oleamide, 50 mg | sc-358696B | 50 mg | $122.00 | |||
Oleamide, 100 mg | sc-358696C | 100 mg | $214.00 | |||
Oleamide, 500 mg | sc-358696D | 500 mg | $627.00 |