Olanzapine Thiolactam Impurity (CAS 1017241-36-9)
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Olanzapine Thiolactam, an impurity of Olanzapine, is of interest in cellular pharmacology primarily for its binding properties. It shows potential for interacting differently with central nervous system receptors. This impurity can influence studies involving neurotransmitter systems, particularly those related to dopamine and serotonin. By potentially altering receptor binding, this compound offers a unique tool for exploring receptor dynamics and drug-receptor interaction mechanisms. It may also serve as a useful control in pharmacological research, helping to distinguish effects due to the parent compound from those of its metabolites. The stability of the thiolactam ring in cellular environments can impact the compound′s pharmacokinetics and metabolism.
Olanzapine Thiolactam Impurity (CAS 1017241-36-9) References
- Isolation, identification, and synthesis of two oxidative degradation products of olanzapine (LY170053) in solid oral formulations. | Baertschi, SW., et al. 2008. J Pharm Sci. 97: 883-92. PMID: 17879984
- Effects of conformationally restricted 4-piperazinyl-10H-thienobenzodiazepine neuroleptics on central dopaminergic and cholinergic systems. | Chakrabarti, JK., et al. 1982. J Med Chem. 25: 1133-40. PMID: 6128416
Ordering Information
| Product Name | Catalog # | UNIT | Price | Qty | FAVORITES | |
Olanzapine Thiolactam Impurity, 1 mg | sc-361833 | 1 mg | $377.00 | |||
Olanzapine Thiolactam Impurity, 2 mg | sc-361833C | 2 mg | $622.00 | |||
Olanzapine Thiolactam Impurity, 5 mg | sc-361833A | 5 mg | $1132.00 | |||
Olanzapine Thiolactam Impurity, 10 mg | sc-361833D | 10 mg | $1642.00 | |||
Olanzapine Thiolactam Impurity, 25 mg | sc-361833B | 25 mg | $3070.00 |