Date published: 2026-4-1

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Octyl β-D-Lactoside (CAS 74513-17-0)

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Application:
Octyl β-D-Lactoside is used in the solubilization of membrane bound protein
CAS Number:
74513-17-0
Molecular Weight:
437.51
Molecular Formula:
C20H37O10
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

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Octyl β-D-Lactoside is a non-ionic detergent commonly utilized in biochemical and biophysical research due to its unique properties and versatile applications. This chemical is known for its ability to solubilize and stabilize membrane proteins, making it a valuable tool in studying their structure, function, and interactions. Octyl β-D-Lactoside interacts with lipid bilayers, disrupting membrane integrity and facilitating the extraction of membrane-bound proteins while maintaining their native conformation. Furthermore, it has been extensively used in membrane protein crystallization studies, where the detergent plays a crucial role in maintaining protein stability and promoting crystal growth. Additionally, Octyl β-D-Lactoside has found applications in various biophysical techniques, such as nuclear magnetic resonance (NMR) spectroscopy and electron microscopy, for investigating membrane protein dynamics and organization. Its mild detergent properties and compatibility with a wide range of experimental conditions make Octyl β-D-Lactoside a preferred choice for researchers studying membrane proteins in both basic and applied research settings. Overall, this chemical serves as an essential tool in elucidating the structure-function relationships of membrane proteins and advancing our understanding of cellular processes at the molecular level.


Octyl β-D-Lactoside (CAS 74513-17-0) References

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  2. Isolation and characterization of ceramide glycanase from the leech, Macrobdella decora.  |  Zhou, B., et al. 1989. J Biol Chem. 264: 12272-7. PMID: 2745442
  3. Site-Selective, Copper-Mediated O-Arylation of Carbohydrate Derivatives.  |  Dimakos, V., et al. 2017. J Am Chem Soc. 139: 15515-15521. PMID: 29058424
  4. Sialylation of n-alkyllactosides, galactosides and glucosides by sialyltransferases from rat liver Golgi vesicles.  |  Pohlentz, G., et al. 1994. Glycobiology. 4: 625-31. PMID: 7881177

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Octyl β-D-Lactoside, 100 mg

sc-222094
100 mg
$380.00