Date published: 2025-11-1

1-800-457-3801

SCBT Portrait Logo
Seach Input

Octreotide Acetate (CAS 79517-01-4)

0.0(0)
Write a reviewAsk a question

Alternate Names:
D-Phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-[(1R,2R)-2-hydroxy-1-(hydroxymethyl)propyl]-L-cysteinamide Cyclic (2-7)-Disulfide Acetate
Application:
Octreotide Acetate is an octapeptide analog of Somatostatin
CAS Number:
79517-01-4
Molecular Weight:
1079.29
Molecular Formula:
C51H70N10O12S2
For Research Use Only. Not Intended for Diagnostic or Therapeutic Use.
* Refer to Certificate of Analysis for lot specific data.

QUICK LINKS

Octreotide acetate is a synthetic analog of somatostatin, a peptide hormone that naturally inhibits the secretion of several other hormones, including growth hormone (GH), thyroid-stimulating hormone (TSH), and certain gastrointestinal hormones. Structurally designed to mimic the effects of natural somatostatin but with greater potency and significantly extended duration of action, octreotide acetate exerts its effects by binding to somatostatin receptors, primarily found in the pituitary and the gastrointestinal tract. This binding initiates a cascade of intracellular processes leading to the inhibition of hormone secretion. The extended activity of octreotide acetate, compared to somatostatin, is due to its resistance to enzymatic degradation, making it particularly valuable in research applications for studying hormonal regulation and neuroendocrine functions. Additionally, its ability to precisely modulate the release of various hormones makes it a useful tool in the study of diseases characterized by hormonal imbalances, providing insight into potential mechanisms of disease progression and associated physiological changes.


Octreotide Acetate (CAS 79517-01-4) References

  1. Acute in vivo effect of octreotide acetate, a somatostatin analogue on the cellular function of gastric mucosa in the rat.  |  Motegi, M., et al. 1998. J Gastroenterol Hepatol. 13: 220-4. PMID: 10221827
  2. LC determination of octreotide acetate in compound formulations of Sandostatin and diamorphine hydrochloride.  |  Kyaterekera, N., et al. 1999. J Pharm Biomed Anal. 21: 327-30. PMID: 10703987
  3. Effects of octreotide acetate and Saccharomyces boulardii on bacterial translocation in an experimental intestinal loop obstruction model of rats.  |  Aldemir, M., et al. 2002. Tohoku J Exp Med. 198: 1-9. PMID: 12498309
  4. Ciliary body toxicity of cyclosporin A and octreotide acetate in rabbit eyes: a comparison with mitomycin C and 5-fluorouracil.  |  Akyol, N., et al. 2003. Graefes Arch Clin Exp Ophthalmol. 241: 816-22. PMID: 13680250
  5. Mechanistic evaluation of the glucose-induced reduction in initial burst release of octreotide acetate from poly(D,L-lactide-co-glycolide) microspheres.  |  Wang, J., et al. 2004. Biomaterials. 25: 1919-27. PMID: 14738856
  6. Oral delivery of octreotide acetate in Intravail® improves uptake, half-life, and bioavailability over subcutaneous administration in male Swiss webster mice.  |  Maggio, ET. and Grasso, P. 2011. Regul Pept. 167: 233-8. PMID: 21329733
  7. A rapid hydrolysis method and DABS-Cl derivatization for complete amino acid analysis of octreotide acetate by reversed phase HPLC.  |  Akhlaghi, Y., et al. 2015. Amino Acids. 47: 2255-63. PMID: 26002809
  8. Treatment of Gastrin-Secreting Tumor With Sustained-Release Octreotide Acetate in a Dog.  |  Kim, S., et al. 2015. J Am Anim Hosp Assoc. 51: 407-12. PMID: 26535461
  9. Quantitative determination and validation of octreotide acetate using 1 H-NMR spectroscopy with internal standard method.  |  Yu, C., et al. 2018. Magn Reson Chem. 56: 37-45. PMID: 28921691
  10. Fragmented particles containing octreotide acetate prepared by spray drying technique for dry powder inhalation.  |  Hou, A., et al. 2018. Drug Deliv Transl Res. 8: 693-701. PMID: 29600480
  11. Effect of current magnitude and drug concentration on iontophoretic delivery of octreotide acetate (Sandostatin) in the rabbit.  |  Lau, DT., et al. 1994. Pharm Res. 11: 1742-6. PMID: 7899238
  12. Effect of somatostatin and octreotide acetate on OP-CCK-stimulated exocrine secretion in the denervated canine pancreas.  |  Garvin, PJ., et al. 1996. Pancreas. 13: 304-10. PMID: 8884853
  13. Effect of a somatostatin analog (octreotide acetate) on the growth of retinal pigment epithelial cells in culture.  |  Luo, Q., et al. 1996. Curr Eye Res. 15: 909-13. PMID: 8921210
  14. Octreotide acetate inhibits motility in the rabbit distal colon.  |  John, KD., et al. 1997. Eur Surg Res. 29: 311-8. PMID: 9257104

Ordering Information

Product NameCatalog #UNITPriceQtyFAVORITES

Octreotide Acetate, 10 mg

sc-397566
10 mg
$367.00

Octreotide Acetate, 25 mg

sc-397566A
25 mg
$445.00

Octreotide Acetate, 50 mg

sc-397566B
50 mg
$560.00